AIMC Topic: Autism Spectrum Disorder

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A comparison of machine learning algorithms for the surveillance of autism spectrum disorder.

PloS one
OBJECTIVE: The Centers for Disease Control and Prevention (CDC) coordinates a labor-intensive process to measure the prevalence of autism spectrum disorder (ASD) among children in the United States. Random forests methods have shown promise in speedi...

Multi-view learning-based data proliferator for boosting classification using highly imbalanced classes.

Journal of neuroscience methods
BACKGROUND: Multi-view data representation learning explores the relationship between the views and provides rich complementary information that can improve computer-aided diagnosis. Specifically, existing machine learning methods devised to automate...

Assisted therapeutic system based on reinforcement learning for children with autism.

Computer assisted surgery (Abingdon, England)
Assisted therapy is increasingly used in autism spectrum disorders (ASD) for improving social interaction and communication skills in recent years. A lot of studies have proven that the form of interactive games for therapy has a good effect on child...

Computer- and Robot-Assisted Therapies to Aid Social and Intellectual Functioning of Children with Autism Spectrum Disorder.

Medicina (Kaunas, Lithuania)
BACKGROUND AND OBJECTIVES: Children with autism spectrum disorder (ASD) experience challenges with social interactions, a core feature of the disorder. Social skills therapy has been shown to be helpful. Over the past several years, computer-assisted...

From pattern classification to stratification: towards conceptualizing the heterogeneity of Autism Spectrum Disorder.

Neuroscience and biobehavioral reviews
Pattern classification and stratification approaches have increasingly been used in research on Autism Spectrum Disorder (ASD) over the last ten years with the goal of translation towards clinical applicability. Here, we present an extensive scoping ...

The "MS-ROM/IFAST" Model, a Novel Parallel Nonlinear EEG Analysis Technique, Distinguishes ASD Subjects From Children Affected With Other Neuropsychiatric Disorders With High Degree of Accuracy.

Clinical EEG and neuroscience
. In a previous study, we showed a new EEG processing methodology called Multi-Scale Ranked Organizing Map/Implicit Function As Squashing Time (MS-ROM/IFAST) performing an almost perfect distinction between computerized EEG of Italian children with a...

Estimation of allele-specific fitness effects across human protein-coding sequences and implications for disease.

Genome research
A central challenge in human genomics is to understand the cellular, evolutionary, and clinical significance of genetic variants. Here, we introduce a unified population-genetic and machine-learning model, called inear llele-pecific election nferenc ...

Ensemble learning with 3D convolutional neural networks for functional connectome-based prediction.

NeuroImage
The specificity and sensitivity of resting state functional MRI (rs-fMRI) measurements depend on preprocessing choices, such as the parcellation scheme used to define regions of interest (ROIs). In this study, we critically evaluate the effect of bra...

Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk.

Nature genetics
We address the challenge of detecting the contribution of noncoding mutations to disease with a deep-learning-based framework that predicts the specific regulatory effects and the deleterious impact of genetic variants. Applying this framework to 1,7...

nCREANN: Nonlinear Causal Relationship Estimation by Artificial Neural Network; Applied for Autism Connectivity Study.

IEEE transactions on medical imaging
Quantifying causal (effective) interactions between different brain regions are very important in neuroscience research. Many conventional methods estimate effective connectivity based on linear models. However, using linear connectivity models may o...