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Bayes Theorem

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Machine learning-enhanced noninvasive prenatal testing of monogenic disorders.

Prenatal diagnosis
OBJECTIVE: Single-nucleotide variants (SNVs) are of great significance in prenatal diagnosis as they are the leading cause of inherited single-gene disorders (SGDs). Identifying SNVs in a non-invasive prenatal screening (NIPS) scenario is particularl...

Identification and Connectomic Profiling of Concussion Using Bayesian Machine Learning.

Journal of neurotrauma
Accurate early diagnosis of concussion is useful to prevent sequelae and improve neurocognitive outcomes. Early after head impact, concussion diagnosis may be doubtful in persons whose neurological, neuroradiological, and/or neurocognitive examinatio...

Bidirectional machine learning-assisted sensitivity-based stochastic searching approach for groundwater DNAPL source characterization.

Environmental science and pollution research international
In this study, we designed a machine learning-based parallel global searching method using the Bayesian inversion framework for efficient identification of dense non-aqueous phase liquid (DNAPL) source characteristics and contaminant transport parame...

Leveraging machine learning: Covariate-adjusted Bayesian adaptive randomization and subgroup discovery in multi-arm survival trials.

Contemporary clinical trials
Clinical trials evaluate the safety and efficacy of treatments for specific diseases. Ensuring these studies are well-powered is crucial for identifying superior treatments. With the rise of personalized medicine, treatment efficacy may vary based on...

Sorption Behavior of Azo Dye Congo Red onto Activated Biochar from Waste: Gradient Boosting Machine Learning-Assisted Bayesian Optimization for Improved Adsorption Process.

International journal of molecular sciences
This work aimed to describe the adsorption behavior of Congo red (CR) onto activated biochar material prepared from waste (). The carbon precursor was soaked with phosphoric acid, followed by pyrolysis to convert the precursor into activated biochar...

Construction and validation of an algorithm to separate focal and generalised epilepsy using clinical variables: A comparison of machine learning approaches.

Epilepsy & behavior : E&B
PURPOSE: Epilepsy type, whether focal or generalised, is important in deciding anti-seizure medication (ASM). In resource-limited settings, investigations are usually not available, so a clinical separation is required. We used a naïve Bayes approach...

Predicting FFAR4 agonists using structure-based machine learning approach based on molecular fingerprints.

Scientific reports
Free Fatty Acid Receptor 4 (FFAR4), a G-protein-coupled receptor, is responsible for triggering intracellular signaling pathways that regulate various physiological processes. FFAR4 agonists are associated with enhancing insulin release and mitigatin...

Developing an interpretation model for body fluid identification.

Forensic science international
Criminal investigations, particularly sexual assaults, frequently require the identification of body fluid type in addition to body fluid donor to provide context. In most cases this can be achieved by conventional methods, however, in certain scenar...

Sequence based model using deep neural network and hybrid features for identification of 5-hydroxymethylcytosine modification.

Scientific reports
RNA modifications are pivotal in the development of newly synthesized structures, showcasing a vast array of alterations across various RNA classes. Among these, 5-hydroxymethylcytosine (5HMC) stands out, playing a crucial role in gene regulation and...

Advancing post-traumatic seizure classification and biomarker identification: Information decomposition based multimodal fusion and explainable machine learning with missing neuroimaging data.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
A late post-traumatic seizure (LPTS), a consequence of traumatic brain injury (TBI), can potentially evolve into a lifelong condition known as post-traumatic epilepsy (PTE). Presently, the mechanism that triggers epileptogenesis in TBI patients remai...