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Biocompatible Materials

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Modeling and Optimization for a New Compliant 2-dof Stage for Locating Biomaterial Samples by an Efficient Approach of a Kinetostatic Analysis-Based Method and Neural Network Algorithm.

Computational intelligence and neuroscience
The nanoindentation technique is employed to characterize the behaviors of biomaterials. Nevertheless, there is a lack of development of a miniaturized precise positioner for in situ nanoindentation. Besides, modeling behaviors of the positioner are ...

Discovering design principles of collagen molecular stability using a genetic algorithm, deep learning, and experimental validation.

Proceedings of the National Academy of Sciences of the United States of America
Collagen is the most abundant structural protein in humans, providing crucial mechanical properties, including high strength and toughness, in tissues. Collagen-based biomaterials are, therefore, used for tissue repair and regeneration. Utilizing col...

CollagenTransformer: End-to-End Transformer Model to Predict Thermal Stability of Collagen Triple Helices Using an NLP Approach.

ACS biomaterials science & engineering
Collagen is one of the most important structural proteins in biology, and its structural hierarchy plays a crucial role in many mechanically important biomaterials. Here, we demonstrate how transformer models can be used to predict, directly from the...

Leveraging IoT-Aware Technologies and AI Techniques for Real-Time Critical Healthcare Applications.

Sensors (Basel, Switzerland)
Personalised healthcare has seen significant improvements due to the introduction of health monitoring technologies that allow wearable devices to unintrusively monitor physiological parameters such as heart health, blood pressure, sleep patterns, an...

Emerging Magnetic Fabrication Technologies Provide Controllable Hierarchically-Structured Biomaterials and Stimulus Response for Biomedical Applications.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Multifunctional nanocomposites which exhibit well-defined physical properties and encode spatiotemporally-controlled responses are emerging as components for advanced responsive systems. For biomedical applications magnetic nanocomposite materials ha...

Robot-assisted in situ bioprinting of gelatin methacrylate hydrogels with stem cells induces hair follicle-inclusive skin regeneration.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Large skin defects caused by accidents or disease can cause fluid loss, water and electrolyte disorders, hypoproteinemia and serious infection and remain a difficult problem in clinical practice. In situ bioprinting is a promising, recently developed...

Advances in materials-based therapeutic strategies against osteoporosis.

Biomaterials
Osteoporosis is caused by the disruption in homeostasis between bone formation and bone resorption. Conventional management of osteoporosis involves systematic drug administration and hormonal therapy. These treatment strategies have limited curative...

Advanced Soft Robotic System for In Situ 3D Bioprinting and Endoscopic Surgery.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Three-dimensional (3D) bioprinting technology offers great potential in the treatment of tissue and organ damage. Conventional approaches generally rely on a large form factor desktop bioprinter to create in vitro 3D living constructs before introduc...

Exploring the Potential of GPT-4 in Biomedical Engineering: The Dawn of a New Era.

Annals of biomedical engineering
Biomedical engineering is a relatively young interdisciplinary field based on engineering, biology, and medicine. Of note, the rapid progress of artificial intelligence (AI)-based technologies has made a significant impact on the biomedical engineeri...

De Novo Design of Polyhedral Protein Assemblies: Before and After the AI Revolution.

Chembiochem : a European journal of chemical biology
Self-assembling polyhedral protein biomaterials have gained attention as engineering targets owing to their naturally evolved sophisticated functions, ranging from protecting macromolecules from the environment to spatially controlling biochemical re...