BACKGROUND: Dimension reduction, especially feature selection, is an important step in improving classification performance for high-dimensional data. Particularly in cancer research, when reducing the number of features, i.e., genes, it is important...
Robot-assisted total hip arthroplasty (R-THA) is increasingly being performed throughout the world. The invasiveness of this operation is unknown. We retrospectively reviewed the cohort of consecutive osteonecrosis of the femoral head (ONFH) patients...
In the recent JAVELIN Bladder 100 phase 3 trial, avelumab plus best supportive care significantly prolonged overall survival relative to best supportive care alone as first-line maintenance therapy following first-line platinum-based chemotherapy in ...
BACKGROUND: Biomarker discovery exploiting feature importance of machine learning has risen recently in the microbiome landscape with its high predictive performance in several disease states. To have a concrete selection among a high number of featu...
Ophthalmic biomarkers have long played a critical role in diagnosing and managing ocular diseases. Oculomics has emerged as a field that utilizes ocular imaging biomarkers to provide insights into systemic diseases. Advances in diagnostic and imaging...
Biochimica et biophysica acta. Reviews on cancer
Oct 18, 2023
Recent multi-omics studies, including proteomics, transcriptomics, genomics, and metabolomics have revealed the critical role of post-translational modifications (PTMs) in the progression and pathogenesis of Glioblastoma multiforme (GBM). Further, PT...
Neural networks : the official journal of the International Neural Network Society
Oct 14, 2023
This paper analyzes diverse features extracted from spoken language to select the most discriminative ones for dementia detection. We present a two-step feature selection (FS) approach: Step 1 utilizes filter methods to pre-screen features, and Step ...
BACKGROUND: Alzheimer's disease (AD) is an incurable, debilitating neurodegenerative disorder. Current biomarkers for AD diagnosis require expensive neuroimaging or invasive cerebrospinal fluid sampling, thus precluding early detection. Blood-based b...
Aortic aneurysm is a life-threatening condition and mechanisms underlying its formation and progression are still incompletely understood. Omics approach has brought new insights to identify a broad spectrum of biomarkers and better understand cellul...
IEEE/ACM transactions on computational biology and bioinformatics
Oct 9, 2023
The circRNAs and miRNAs play an important role in the development of human diseases, and they can be widely used as biomarkers of diseases for disease diagnosis. In particular, circRNAs can act as sponge adsorbers for miRNAs and act together in certa...
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