AIMC Topic: CD68 Molecule

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3-Dimensional morphological characterization of neuroretinal microglia in Alzheimer's disease via machine learning.

Acta neuropathologica communications Dec 24, 2024
Alzheimer's Disease (AD) is a debilitating neurodegenerative disease that affects 47.5 million people worldwide. AD is characterised by the formation of plaques containing extracellular amyloid-β (Aβ) and neurofibrillary tangles composed of hyper-pho...
Humans Machine Learning Female Aged Aged, 80 and over Male Middle Aged Imaging, Three-Dimensional Microglia Antigens, CD Retina Alzheimer Disease Calcium-Binding Proteins Microfilament Proteins Antigens, Differentiation, Myelomonocytic CD68 Molecule
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Integrating machine learning algorithms and single-cell analysis to identify gut microbiota-related macrophage biomarkers in atherosclerotic plaques.

Frontiers in cellular and infection microbiology Apr 23, 2024
OBJECTIVE: The relationship between macrophages and the gut microbiota in patients with atherosclerosis remains poorly defined, and effective biological markers are lacking. This study aims to elucidate the interplay between gut microbial communities...
Humans Machine Learning Algorithms Macrophages Biomarkers Gene Expression Profiling Single-Cell Analysis Gene Regulatory Networks Gastrointestinal Microbiome Antigens, CD Atherosclerosis Plaque, Atherosclerotic Agammaglobulinaemia Tyrosine Kinase Antigens, Differentiation, Myelomonocytic Interferon Regulatory Factors Receptors, CCR1 CD68 Molecule
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