AIMC Topic: Antigens, CD

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Comprehensive analysis and experimental validation of BST1 as a novel diagnostic biomarker for pediatric sepsis using multiple machine learning algorithms.

European journal of pediatrics
Bone marrow stromal cell antigen-1 (BST1) expression is elevated in a variety of human diseases, but its relationship with pediatric sepsis is unclear. This study aimed to investigate the expression of BST1 in pediatric sepsis patients and its value ...

3-Dimensional morphological characterization of neuroretinal microglia in Alzheimer's disease via machine learning.

Acta neuropathologica communications
Alzheimer's Disease (AD) is a debilitating neurodegenerative disease that affects 47.5 million people worldwide. AD is characterised by the formation of plaques containing extracellular amyloid-β (Aβ) and neurofibrillary tangles composed of hyper-pho...

Analysis of the basement membrane-related genes ITGA7 and its regulatory role in periodontitis via machine learning: a retrospective study.

BMC oral health
BACKGROUND: Periodontitis is among the most prevalent inflammatory conditions and greatly impacts oral health. This study aimed to elucidate the role of basement membrane-related genes in the pathogenesis and diagnosis of periodontitis.

Unveiling the intricate interplay: Exploring biological bridges between renal ischemia-reperfusion injury and T cell-mediated immune rejection in kidney transplantation.

PloS one
UNLABELLED: Although the link between ischemia-reperfusion injury (IRI) and T cell-mediated rejection (TCMR) in kidney transplantation (KT) is well known, the mechanism remains unclear. We investigated essential genes and biological processes involve...

Hypothesis-free deep survival learning applied to the tumour microenvironment in gastric cancer.

The journal of pathology. Clinical research
The biological complexity reflected in histology images requires advanced approaches for unbiased prognostication. Machine learning and particularly deep learning methods are increasingly applied in the field of digital pathology. In this study, we p...

Current Projection Methods-Induced Biases at Subgroup Detection for Machine-Learning Based Data-Analysis of Biomedical Data.

International journal of molecular sciences
Advances in flow cytometry enable the acquisition of large and high-dimensional data sets per patient. Novel computational techniques allow the visualization of structures in these data and, finally, the identification of relevant subgroups. Correct ...

Machine learning for the detection of early immunological markers as predictors of multi-organ dysfunction.

Scientific data
The immune response to major trauma has been analysed mainly within post-hospital admission settings where the inflammatory response is already underway and the early drivers of clinical outcome cannot be readily determined. Thus, there is a need to ...