AIMC Topic: Interferon Regulatory Factors

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Identification and validation of programmed cell death related biomarkers for the treatment and prevention COVID-19.

Annals of medicine Apr 29, 2025
PURPOSE: Programmed cell death (PCD) plays a key role in the progression of coronavirus disease 2019 (COVID-19). However, PCD-relevant biomarkers have not been fully discovered. The aim of this study was to explore the PCD-relevant biomarkers for the...
Humans COVID-19 Biomarkers Female SARS-CoV-2 Aged Adult Male Middle Aged Gene Expression Profiling Computational Biology Apoptosis Matrix Metalloproteinase 9 Interferon Regulatory Factors
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Integrating machine learning algorithms and single-cell analysis to identify gut microbiota-related macrophage biomarkers in atherosclerotic plaques.

Frontiers in cellular and infection microbiology Apr 23, 2024
OBJECTIVE: The relationship between macrophages and the gut microbiota in patients with atherosclerosis remains poorly defined, and effective biological markers are lacking. This study aims to elucidate the interplay between gut microbial communities...
Humans Machine Learning Algorithms Macrophages Biomarkers Gene Expression Profiling Single-Cell Analysis Gene Regulatory Networks Gastrointestinal Microbiome Antigens, CD Atherosclerosis Plaque, Atherosclerotic Agammaglobulinaemia Tyrosine Kinase Antigens, Differentiation, Myelomonocytic Interferon Regulatory Factors Receptors, CCR1 CD68 Molecule
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Genetic Risk Assessment of Nonsyndromic Cleft Lip with or without Cleft Palate by Linking Genetic Networks and Deep Learning Models.

International journal of molecular sciences Feb 25, 2023
Recent deep learning algorithms have further improved risk classification capabilities. However, an appropriate feature selection method is required to overcome dimensionality issues in population-based genetic studies. In this Korean case-control st...
Humans Risk Factors Risk Assessment Case-Control Studies Deep Learning Gene Regulatory Networks Genetic Predisposition to Disease Polymorphism, Single Nucleotide Genotype Cleft Lip Cleft Palate Interferon Regulatory Factors
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