AIMC Topic: Cell Cycle Checkpoints

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A potential new strategy for BC treatment: NPs containing solanine and evaluation of its anticancer and antimetastatic properties.

BMC cancer May 12, 2025
Solanine has been shown to inhibit cancer by regulating the expression of apoptosis (Bax, Bcl-2) and metastasis (CDH-1, MMP2) genes in various cancer cell types. We synthesized optimized niosome NPs (NPs) with high solubility and capacity for solanin...
Cell Proliferation Apoptosis Nanoparticles Cell Cycle Checkpoints Solanine Liposomes MCF-7 Cells Breast Neoplasms Cell Line, Tumor Antineoplastic Agents Humans Female
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Piperidine based 1,2,3-triazolylacetamide derivatives induce cell cycle arrest and apoptotic cell death in .

Journal of advanced research Nov 10, 2020
The fungal pathogen , is a serious threat to public health and is associated with bloodstream infections causing high mortality particularly in patients with serious medical problems. As this pathogen is generally resistant to all the available clas...
Triazoles Apoptosis Antifungal Agents Piperidines Candida Humans Cell Cycle Checkpoints Cell Survival Microbial Sensitivity Tests Candidiasis DNA Damage Acetamides Drug Resistance, Fungal Public Health
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Vitamin E (α-Tocopherol) Exhibits Antitumour Activity on Oral Squamous Carcinoma Cells ORL-48.

Integrative cancer therapies Nov 10, 2016
Cancers involving the oral cavity, head, and neck regions are often treated with cisplatin. In cancer therapy, the main target is to eliminate unwanted cancerous cells. However, reports on the nonselective nature of this drug have raised few concerns...
Cisplatin alpha-Tocopherol Apoptosis Annexin A5 G1 Phase Vitamin E Cell Cycle Checkpoints Cell Line, Tumor Antioxidants Oxidative Stress Carcinoma, Squamous Cell Antineoplastic Agents Resting Phase, Cell Cycle Humans
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[Chemical constituents of liquid culture of symbiotic Chaetomium globosum ML-4 of oyster and their in vitro antitumor activity].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica Nov 1, 2017
Isolation and purification of chemical constituents of liquid culture of symbiotic Chaetomium globosum ML-4 of oyster was performed through silica gel column chromatography, gel filtration over Sephadex LH-20, preparative TLC and HPLC. Five compounds...
Animals Liver Neoplasms Cell Line, Tumor Humans Cell Cycle Checkpoints Phosphatidylinositol 3-Kinases Signal Transduction Ostreidae Carcinoma, Hepatocellular Chaetomium Apoptosis
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