INTRODUCTION: Schizophrenia is a complex mental disorder whose pathophysiology remains elusive, particularly in the roles of subcortex. This study aims to explore the role of subcortex and insula and their relationship with symptom changes in first-e...
The Developing Human Connectome Project (dHCP) aims to explore developmental patterns of the human brain during the perinatal period. An automated processing pipeline has been developed to extract high-quality cortical surfaces from structural brain ...
Functional near-infrared spectroscopy (fNIRS) measures cortical hemodynamic changes, yet it cannot collect this information from subcortical structures, such as the thalamus, which is involved in several key functional networks. To address this drawb...
Medical & biological engineering & computing
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The cortical surface parcellation provides prior guidance for studying mental disorders and human cognition. Graph neural networks (GNNs) have gained popularity in this task to preserve its spatial structure. However, previous GNNs struggled to effec...
Sulci are a fundamental part of brain morphology, closely linked to brain function, cognition, and behavior. Tertiary sulci, characterized as the shallowest and smallest subtype, pose a challenging task for detection. The diagonal sulcus (ds), locate...
Macroscale neuroimaging results have revealed significant differences in the structural and functional connectivity patterns of gyri and sulci in the primate cerebral cortex. Despite these findings, understanding these differences at the molecular le...
Accurately predicting individual antidepressant treatment response could expedite the lengthy trial-and-error process of finding an effective treatment for major depressive disorder (MDD). We tested and compared machine learning-based methods that pr...
Cortical parcellation delineates the cerebral cortex into distinct regions according to their distinctiveness in anatomy and/or function, which is a fundamental preprocess in brain cortex analysis and can influence the accuracy and specificity of sub...
Current artificial systems suffer from catastrophic forgetting during continual learning, a limitation absent in biological systems. Biological mechanisms leverage the dual representation of specific and generalized memories within corticohippocampal...
The identification of cortical sulci is key for understanding functional and structural development of the cortex. While large, consistent sulci (or primary/secondary sulci) receive significant attention in most studies, the exploration of smaller an...