AIMC Topic: Chromosomes, Human, Pair 9

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Whole-genome sequencing reveals individual and cohort level insights into chromosome 9p syndromes.

Genome medicine Oct 24, 2025
BACKGROUND: Previous genomic efforts on chromosome 9p deletion and duplication syndromes have utilized low-resolution strategies (i.e., karyotypes, chromosome microarrays). These studies have provided important initial insights into these syndromes. ...
Humans Female Animals Male Cohort Studies Mice DNA Copy Number Variations Syndrome Whole Genome Sequencing Chromosome Deletion Chromosome Disorders Chromosomes, Human, Pair 9
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Identification of genomic alteration and prognosis using pathomics-based artificial intelligence in oral leukoplakia and head and neck squamous cell carcinoma: a multicenter experimental study.

International journal of surgery (London, England) Jan 1, 2025
BACKGROUND: Loss of chromosome 9p is an important biomarker in the malignant transformation of oral leukoplakia (OLK) to head and neck squamous cell carcinoma (HNSCC), and is associated with the prognosis of HNSCC patients. However, various challenge...
Humans Artificial Intelligence Prognosis Retrospective Studies Female Aged Adult Male Middle Aged Genomics Squamous Cell Carcinoma of Head and Neck Head and Neck Neoplasms Leukoplakia, Oral Chromosomes, Human, Pair 9
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