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Leukoplakia, Oral

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Prediction of the risk of cancer and the grade of dysplasia in leukoplakia lesions using deep learning.

Oral oncology
OBJECTIVES: To estimate the probability of malignancy of an oral leukoplakia lesion using Deep Learning, in terms of evolution to cancer and high-risk dysplasia.

[Agreement evaluation of the severity of oral epithelial dysplasia in oral leukoplakia].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
To evaluate the inter-observer agreement of the severity of oral epithelial dysplasia in oral leukoplakia, providing a theoretical basis for the development of a more objective grading system. This study included 60 digital pathological slides of o...

Deep learning-based pathology image analysis predicts cancer progression risk in patients with oral leukoplakia.

Cancer medicine
BACKGROUND: Oral leukoplakia (OL) is associated with an increased risk for oral cancer (OC) development. Prediction of OL cancer progression may contribute to decreased OC morbidity and mortality by favoring early intervention. Current OL progression...

Oral epithelial dysplasia detection and grading in oral leukoplakia using deep learning.

BMC oral health
BACKGROUND: The grading of oral epithelial dysplasia is often time-consuming for oral pathologists and the results are poorly reproducible between observers. In this study, we aimed to establish an objective, accurate and useful detection and grading...

Detection of oral cancer and oral potentially malignant disorders using artificial intelligence-based image analysis.

Head & neck
BACKGROUND: We aimed to construct an artificial intelligence-based model for detecting oral cancer and dysplastic leukoplakia using oral cavity images captured with a single-lens reflex camera.

Prediction of the short-term efficacy and recurrence of photodynamic therapy in the treatment of oral leukoplakia based on deep learning.

Photodiagnosis and photodynamic therapy
BACKGROUND: The treatment of oral leukoplakia (OLK) with aminolaevulinic acid photodynamic therapy (ALA-PDT) is widespread. Nonetheless, there is variation in efficacy. Therefore, this study constructed a model for predicting the short-term efficacy ...

A Deep Learning System to Predict Epithelial Dysplasia in Oral Leukoplakia.

Journal of dental research
Oral leukoplakia (OL) has an inherent disposition to develop oral cancer. OL with epithelial dysplasia (OED) is significantly likely to undergo malignant transformation; however, routine OED assessment is invasive and challenging. This study investig...

Artificial intelligence for image recognition in diagnosing oral and oropharyngeal cancer and leukoplakia.

Scientific reports
Visual diagnosis is one of the key features of squamous cell carcinoma of the oral cavity (OSCC) and oropharynx (OPSCC), both subsets of head and neck squamous cell carcinoma (HNSCC) with a heterogeneous clinical appearance. Advancements in artificia...

Identification of genomic alteration and prognosis using pathomics-based artificial intelligence in oral leukoplakia and head and neck squamous cell carcinoma: a multicenter experimental study.

International journal of surgery (London, England)
BACKGROUND: Loss of chromosome 9p is an important biomarker in the malignant transformation of oral leukoplakia (OLK) to head and neck squamous cell carcinoma (HNSCC), and is associated with the prognosis of HNSCC patients. However, various challenge...

Sub-diffuse Reflectance Spectroscopy Combined With Machine Learning Method for Oral Mucosal Disease Identification.

Lasers in surgery and medicine
OBJECTIVES: Oral squamous cell carcinoma (OSCC) is the sixth-highest incidence of malignant tumors worldwide. However, early diagnosis is complex owing to the impracticality of biopsying every potentially premalignant intraoral lesion. Here, we prese...