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Colonic Neoplasms

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Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy.

Cancer research
Cancer immunotherapy provides durable clinical benefit in only a small fraction of patients, and identifying these patients is difficult due to a lack of reliable biomarkers for prediction and evaluation of treatment response. Here, we demonstrate th...

Systemic inflammatory response in robot-assisted and laparoscopic surgery for colon cancer (SIRIRALS): study protocol of a randomized controlled trial.

BMC surgery
BACKGROUND: Robot-assisted surgery is being increasingly adopted in treating colorectal cancer, and the transition from laparoscopic surgery to robot-assisted surgery is a trend. The evidence of the benefits of robot-assisted surgery is sparse. Howev...

DMFMDA: Prediction of Microbe-Disease Associations Based on Deep Matrix Factorization Using Bayesian Personalized Ranking.

IEEE/ACM transactions on computational biology and bioinformatics
Identifying the microbe-disease associations is conducive to understanding the pathogenesis of disease from the perspective of microbe. In this paper, we propose a deep matrix factorization prediction model (DMFMDA) based on deep neural network. Firs...

Disease type detection in lung and colon cancer images using the complement approach of inefficient sets.

Computers in biology and medicine
Lung and colon cancers are deadly diseases that can develop simultaneously in organs and adversely affect human life in some special cases. Although the frequency of simultaneous occurrence of these two types of cancer is unlikely, there is a high pr...

Deep learning for colon cancer histopathological images analysis.

Computers in biology and medicine
Nowadays, digital pathology plays a major role in the diagnosis and prognosis of tumours. Unfortunately, existing methods remain limited when faced with the high resolution and size of Whole Slide Images (WSIs) coupled with the lack of richly annotat...

Robotic versus laparoscopic right hemicolectomy: a case-matched study.

Journal of robotic surgery
The current gold standard surgical treatment for right colonic malignancy is the laparoscopic right hemicolectomy (LRH). However, laparoscopic surgery has limitations which can be overcome by robotic surgery. The benefits of robotics for rectal cance...

Initial experience with a suprapubic single-port robotic right hemicolectomy in patients with colon cancer.

Techniques in coloproctology
BACKGROUND: We developed a novel suprapubic single-port robotic right hemicolectomy (spRHC) procedure for patients with right colon cancer using a da Vinci SP Surgical System. The aim of this study was to determine the safety and feasibility of this ...

Current status and limitations of artificial intelligence in colonoscopy.

United European gastroenterology journal
BACKGROUND: Artificial intelligence (AI) using deep learning methods for polyp detection (CADe) and characterization (CADx) is on the verge of clinical application. CADe already implied its potential use in randomized controlled trials. Further effor...

Pure Ion Chromatograms Combined with Advanced Machine Learning Methods Improve Accuracy of Discriminant Models in LC-MS-Based Untargeted Metabolomics.

Molecules (Basel, Switzerland)
Untargeted metabolomics based on liquid chromatography coupled with mass spectrometry (LC-MS) can detect thousands of features in samples and produce highly complex datasets. The accurate extraction of meaningful features and the building of discrimi...