AIMC Topic: Computational Biology

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Improved 3-D Protein Structure Predictions using Deep ResNet Model.

The protein journal
Protein Structure Prediction (PSP) is considered to be a complicated problem in computational biology. In spite of, the remarkable progress made by the co-evolution-based method in PSP, it is still a challenging and unresolved problem. Recently, alon...

Evaluating Deep Neural Network Architectures with Transfer Learning for Pneumonitis Diagnosis.

Computational and mathematical methods in medicine
Pneumonitis is an infectious disease that causes the inflammation of the air sac. It can be life-threatening to the very young and elderly. Detection of pneumonitis from X-ray images is a significant challenge. Early detection and assistance with dia...

Gastrointestinal Tract Disease Classification from Wireless Endoscopy Images Using Pretrained Deep Learning Model.

Computational and mathematical methods in medicine
Wireless capsule endoscopy is a noninvasive wireless imaging technology that becomes increasingly popular in recent years. One of the major drawbacks of this technology is that it generates a large number of photos that must be analyzed by medical pe...

A Hybrid Method to Predict Postoperative Survival of Lung Cancer Using Improved SMOTE and Adaptive SVM.

Computational and mathematical methods in medicine
Predicting postoperative survival of lung cancer patients (LCPs) is an important problem of medical decision-making. However, the imbalanced distribution of patient survival in the dataset increases the difficulty of prediction. Although the syntheti...

RF-SVM: Identification of DNA-binding proteins based on comprehensive feature representation methods and support vector machine.

Proteins
Protein-DNA interactions play an important role in biological progress, such as DNA replication, repair, and modification processes. In order to have a better understanding of its functions, the one of the most important steps is the identification o...

ReFeaFi: Genome-wide prediction of regulatory elements driving transcription initiation.

PLoS computational biology
Regulatory elements control gene expression through transcription initiation (promoters) and by enhancing transcription at distant regions (enhancers). Accurate identification of regulatory elements is fundamental for annotating genomes and understan...

Influential Usage of Big Data and Artificial Intelligence in Healthcare.

Computational and mathematical methods in medicine
Artificial intelligence (AI) is making computer systems capable of executing human brain tasks in many fields in all aspects of daily life. The enhancement in information and communications technology (ICT) has indisputably improved the quality of pe...

Predictions, Pivots, and a Pandemic: a Review of 2020's Top Translational Bioinformatics Publications.

Yearbook of medical informatics
OBJECTIVES: Provide an overview of the emerging themes and notable papers which were published in 2020 in the field of Bioinformatics and Translational Informatics (BTI) for the International Medical Informatics Association Yearbook.

A machine learning framework for predicting drug-drug interactions.

Scientific reports
Understanding drug-drug interactions is an essential step to reduce the risk of adverse drug events before clinical drug co-prescription. Existing methods, commonly integrating heterogeneous data to increase model performance, often suffer from a hig...

Improved protein relative solvent accessibility prediction using deep multi-view feature learning framework.

Analytical biochemistry
The accurate prediction of the relative solvent accessibility of a protein is critical to understanding its 3D structure and biological function. In this study, a novel deep multi-view feature learning (DMVFL) framework that integrates three differen...