INTRODUCTION: Short response time is critical for future military medical operations in austere settings or remote areas. Such effective patient care at the point of injury can greatly benefit from the integration of semi-autonomous robotic systems. ...
Proceedings of the National Academy of Sciences of the United States of America
Jan 19, 2021
Exon splicing triggered by unpredicted genetic mutation can cause translational variations in neurodegenerative disorders. In this study, we discover Alzheimer's disease (AD)-specific single-nucleotide variants (SNVs) and abnormal exon splicing of ph...
Many fish species gather by the thousands and swim in harmony with seemingly no effort. Large schools display a range of impressive collective behaviors, from simple shoaling to collective migration and from basic predator evasion to dynamic maneuver...
The Journal of bone and joint surgery. American volume
Jan 6, 2021
BACKGROUND: Understanding the interactions between variables that predict prolonged hospital length of stay (LOS) following spine surgery can help uncover drivers of this risk in patients. This study utilized a novel game-theory-based approach to dev...
PURPOSE: We focused on deep learning for a reduction of motion artifacts in MRI. It is difficult to collect a large number of images with and without motion artifacts from clinical images. The purpose of this study was to create motion artifact image...
In silico ADMET models have progressed significantly over the past ~4 decades, but still, the pharmaceutical industry is vexed by the late-stage toxicity failure of lead molecules. This problem of late-stage attrition of the drug candidates because o...
We propose an extended reservoir computer that shows the functional differentiation of neurons. The reservoir computer is developed to enable changing of the internal reservoir using evolutionary dynamics, and we call it an evolutionary reservoir com...
In order to solve the problem of poor robustness of the traditional method of calculating torque in the mechanical model of 7-DOF picking manipulator, this paper proposes a control strategy of calculating torque plus fuzzy compensation by using adapt...
The Journal of clinical endocrinology and metabolism
Jan 1, 2021
CONTEXT: Postoperative hypercortisolemia mandates further therapy in patients with Cushing's disease (CD). Delayed remission (DR) is defined as not achieving postoperative immediate remission (IR), but having spontaneous remission during long-term fo...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2021
Intrinsic and acquired drug resistance is a major challenge in cancer therapy. Synergistic drug combinations could help to overcome drug resistance. However, the number of possible drug combinations is enormous, and it is infeasible to experimentally...
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