AIMC Topic: Computer Simulation

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Optimization of shunting operation plan in large freight train depot based on DQN algorithm.

PloS one Apr 8, 2025
Shunting operation plan is the main daily work of the freight train depot, the optimization of shunting operation plan is of great significance to improve the efficiency of railway operation and production and transportation. In this paper, the deep ...
Railroads Humans Computer Simulation Algorithms Deep Learning Models, Theoretical
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Virtual lung screening trial (VLST): An in silico study inspired by the national lung screening trial for lung cancer detection.

Medical image analysis Apr 5, 2025
Clinical imaging trials play a crucial role in advancing medical innovation but are often costly, inefficient, and ethically constrained. Virtual Imaging Trials (VITs) present a solution by simulating clinical trial components in a controlled, risk-f...
Tomography, X-Ray Computed Female Sensitivity and Specificity Humans Computer Simulation Lung Neoplasms Early Detection of Cancer Radiography, Thoracic Middle Aged Deep Learning Male
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Machine learning-based in-silico analysis identifies signatures of lysyl oxidases for prognostic and therapeutic response prediction in cancer.

Cell communication and signaling : CCS Apr 5, 2025
BACKGROUND: Lysyl oxidases (LOX/LOXL1-4) are crucial for cancer progression, yet their transcriptional regulation, potential therapeutic targeting, prognostic value and involvement in immune regulation remain poorly understood. This study comprehensi...
Neoplasms Protein-Lysine 6-Oxidase Machine Learning Computer Simulation Humans Computational Biology Prognosis Gene Expression Regulation, Neoplastic
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An innovative underdriven multi-degree-of-freedom sea turtle hydrofoil design.

Bioinspiration & biomimetics Apr 4, 2025
This study presents a new design for a multi-degree-of-freedom underdriven mechanism. The aim is to achieve efficient bionic motion of a sea turtle hydrofoil with multi-degrees-of-freedom using a single drive source. The design focuses on the kinemat...
Biomimetics Swimming Equipment Failure Analysis Turtles Robotics Equipment Design Models, Biological Animals Computer-Aided Design Computer Simulation
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Design and Implementation of Pavlovian Associative Memory Based on DNA Neurons.

IEEE transactions on neural networks and learning systems Apr 4, 2025
In the field of biocomputing and neural networks, deoxyribonucleic acid (DNA) strand displacement (DSD) technology performs well in computation, programming, and information processing. In this article, the multiplication gate, addition gate, and thr...
Animals DNA Neurons Neural Networks, Computer Computer Simulation Association Learning Memory Conditioning, Classical Humans
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Reinforcement learning for safe autonomous two-device navigation of cerebral vessels in mechanical thrombectomy.

International journal of computer assisted radiology and surgery Apr 3, 2025
PURPOSE: Autonomous systems in mechanical thrombectomy (MT) hold promise for reducing procedure times, minimizing radiation exposure, and enhancing patient safety. However, current reinforcement learning (RL) methods only reach the carotid arteries, ...
Humans Algorithms Surgery, Computer-Assisted Patient Safety Thrombectomy Computer Simulation Cerebral Arteries
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Parametric cushioning lattice insole based on finite element method and machine learning: A preliminary computational analysis.

Journal of biomechanics Apr 1, 2025
The cushioning performance of insole has always been a critical consideration in its design. While the development of intelligent methods and the emergence of additive manufacturing (AM) technology have enhanced design freedom and convenience, a stan...
Equipment Design Pressure Finite Element Analysis Foot Orthoses Foot Machine Learning Shoes Humans Computer Simulation Biomechanical Phenomena
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The reality of modeling irritable bowel syndrome: progress and challenges.

Expert opinion on drug discovery Mar 31, 2025
INTRODUCTION: Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that is often therapeutically challenging. While research has advanced our understanding of IBS pathophysiology, developing precise models to predict drug response and...
Disease Models, Animal Gastrointestinal Agents Irritable Bowel Syndrome Animals Humans Computer Simulation Drug Development Artificial Intelligence Reproducibility of Results
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Improving realism in abdominal ultrasound simulation combining a segmentation-guided loss and polar coordinates training.

Medical physics Mar 30, 2025
BACKGROUND: Ultrasound (US) simulation helps train physicians and medical students in image acquisition and interpretation, enabling safe practice of transducer manipulation and organ identification. Current simulators generate realistic images from ...
Humans Computer Simulation Image Processing, Computer-Assisted Abdomen Ultrasonography
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Modeling microbiome-trait associations with taxonomy-adaptive neural networks.

Microbiome Mar 29, 2025
The human microbiome, a complex ecosystem of microorganisms inhabiting the body, plays a critical role in human health. Investigating its association with host traits is essential for understanding its impact on various diseases. Although shotgun met...
Metagenomics Computer Simulation Humans Bacteria Neural Networks, Computer Microbiota
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