AIMC Topic: Computer Simulation
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Quantifying urban land cover imperviousness as input for flood simulation using machine learning: South African case study.
Water science and technology : a journal of the International Association on Water Pollution Research
May 16, 2025
The imperviousness of urban surfaces is an important parameter in simulating urban hydrological responses, but quantifying imperviousness can be challenging and time-consuming. In response, this study presents a new framework to efficiently estimate ...
Multi-criteria decision making and its application to in silico discovery of vaccine candidates for Toxoplasma gondii.
Vaccine
May 15, 2025
Vaccine discovery against eukaryotic parasites is not trivial and few exist. Reverse vaccinology is an in silico vaccine discovery approach, designed to identify vaccine candidates from the thousands of protein sequences encoded by a target genome. P...
Computational modelling of biological systems now and then: revisiting tools and visions from the beginning of the century.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
May 8, 2025
Since the turn of the millennium, computational modelling of biological systems has evolved remarkably and sees matured use spanning basic and clinical research. While the topic of the peri-millennial debate about the virtues and limitations of 'redu...
Exploring the evolutionary adaptations of the unique seahorse tail's muscle architecture through modelling and robotic prototyping.
Journal of the Royal Society, Interface
May 7, 2025
Seahorses possess a unique tail muscle architecture that enables efficient grasping and anchoring onto objects. This prehensile ability is crucial for their survival, as it allows them to resist currents, cling to mates during reproduction and remain...
A controller of robot constant force grinding based on proximal policy optimization algorithm.
PloS one
May 7, 2025
In order to solve the problems of high dependence on the accuracy of environmental model and poor environmental adaptability of traditional control methods, the robot constant force grinding controller that based on proximal policy optimization was p...
Efficient, Robust, and Accurate CNN Predictor for Neuronal Activation in Directional Deep Brain Stimulation.
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
May 7, 2025
The programming of clinical deep brain stimulation (DBS) systems involves numerous combinations of stimulation parameters, such as stimulus amplitude, pulse width, and frequency. As more complex electrode designs, such as directional electrodes, are ...
Robust synchronization of reaction-diffusion memristive neural networks with parameter uncertainties and general couplings.
Neural networks : the official journal of the International Neural Network Society
May 6, 2025
This study investigates the robust synchronization of coupled reaction-diffusion memristive neural networks with parameter uncertainties, internal time delays, and general coupling configurations. The proposed synchronization approach relaxes restric...
Multiscale simulations that incorporate patient-specific neural network models of platelet calcium signaling predict diverse thrombotic outcomes under flow.
PLoS computational biology
May 6, 2025
During thrombosis, platelets rapidly deposit and activate on the vessel wall, driving conditions such as myocardial infarction and stroke. The complexity of thrombus formation in pathological flow geometries, along with patient-specific pharmacologic...
XCAT 3.0: A comprehensive library of personalized digital twins derived from CT scans.
Medical image analysis
May 3, 2025
Virtual Imaging Trials (VIT) offer a cost-effective and scalable approach for evaluating medical imaging technologies. Computational phantoms, which mimic real patient anatomy and physiology, play a central role in VITs. However, the current librarie...
Cangrelor and AVN-944 as repurposable candidate drugs for hMPV: analysis entailed by AI-driven in silico approach.
Molecular diversity
May 2, 2025
Human metapneumovirus (hMPV) primarily causes respiratory tract infections in young children and older adults. According to the 2024 Human Pneumonia Etiology Research for Child Health (PERCH) study, hMPV is the second leading common cause of pneumoni...
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