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CX3C Chemokine Receptor 1

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Identification and experimental validation of diagnostic and prognostic genes CX3CR1, PID1 and PTGDS in sepsis and ARDS using bulk and single-cell transcriptomic analysis and machine learning.

Frontiers in immunology 39763654
BACKGROUND: Sepsis is an uncontrolled reaction to infection that causes severe organ dysfunction and is a primary cause of ARDS. Patients suffering both sepsis and ARDS have a poor prognosis and high mortality. However, the mechanisms behind their si...
Animals Biomarkers CX3C Chemokine Receptor 1 Gene Expression Profiling Gene Regulatory Networks Humans Machine Learning Mice Mice, Inbred C57BL Prognosis Respiratory Distress Syndrome Sepsis Single-Cell Analysis Transcriptome
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Identification of KRAS mutation-associated gut microbiota in colorectal cancer and construction of predictive machine learning model.

Microbiology spectrum 38572984
Gut microbiota has demonstrated an increasingly important role in the onset and development of colorectal cancer (CRC). Nonetheless, the association between gut microbiota and KRAS mutation in CRC remains enigmatic. We conducted 16S rRNA sequencing o...
Aged Bacteria Bifidobacterium Colorectal Neoplasms CX3C Chemokine Receptor 1 Feces Female Gastrointestinal Microbiome Humans Machine Learning Male Middle Aged Mutation Proto-Oncogene Proteins p21(ras) RNA, Ribosomal, 16S
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