AIMC Topic: Cyclin-Dependent Kinase Inhibitor p16

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Computerized tumor multinucleation index (MuNI) is prognostic in p16+ oropharyngeal carcinoma.

The Journal of clinical investigation
BACKGROUNDPatients with p16+ oropharyngeal squamous cell carcinoma (OPSCC) are potentially cured with definitive treatment. However, there are currently no reliable biomarkers of treatment failure for p16+ OPSCC. Pathologist-based visual assessment o...

[Role of high mobility group protein B1 in 
IL-1α-induced endothelial cell senescence].

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
To explore the effect of interleukin-1α (IL-1α) on the senescence of human umbilical vein endothelial cells (HUVECs) and the function of high mobility group protein 1 (HMGB1).
 Methods: HUVECs were randomly divided into a control group, a IL-1α group...