AIMC Topic: Cystitis, Interstitial

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Characteristic genes and immune landscape of interstitial cystitis.

PloS one May 28, 2025
BACKGROUND: Interstitial cystitis (IC) was still a disease with the exclusive diagnosis and lacked an effective gold standard. It was of great significance to find diagnostic markers for IC. Our study was aimed to screen characteristic genes via mach...
Humans Machine Learning Algorithms Adaptor Proteins, Signal Transducing Urinary Bladder Cystitis, Interstitial Gene Expression Profiling ROC Curve
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Lipidomic analysis coupled with machine learning identifies unique urinary lipid signatures in patients with interstitial cystitis/bladder pain syndrome.

World journal of urology Apr 18, 2025
PURPOSE: To identify biomarkers for diagnosis and classification of interstitial cystitis/bladder pain syndrome (IC/BPS) by urinary lipidomics coupled with machine learning.
Lipidomics Middle Aged Male Aged Biomarkers Humans Lipids Cystitis, Interstitial Adult Female Machine Learning
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Identification and validation of immune and diagnostic biomarkers for interstitial cystitis/painful bladder syndrome by integrating bioinformatics and machine-learning.

Frontiers in immunology Jan 23, 2025
BACKGROUND: The etiology of interstitial cystitis/painful bladder syndrome (IC/BPS) remains elusive, presenting significant challenges in both diagnosis and treatment. To address these challenges, we employed a comprehensive approach aimed at identif...
Machine Learning Biomarkers Humans Gene Regulatory Networks Computational Biology Cystitis, Interstitial Gene Expression Profiling Transcriptome
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Letter to the editor for the article "Combination of urinary biomarkers and machine-learning models provided a higher predictive accuracy to predict long-term treatment outcomes of patients with interstitial cystitis/bladder pain syndrome".

World journal of urology May 24, 2024
Predictive Value of Tests Cystitis, Interstitial Prognosis Treatment Outcome Machine Learning Humans Biomarkers
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An integrated machine learning framework for developing and validating a diagnostic model of major depressive disorder based on interstitial cystitis-related genes.

Journal of affective disorders May 14, 2024
BACKGROUND: Major depressive disorder (MDD) and interstitial cystitis (IC) are two highly debilitating conditions that often coexist with reciprocal effect, significantly exacerbating patients' suffering. However, the molecular underpinnings linking ...
Cystitis, Interstitial Humans Machine Learning Gene Expression Profiling Transcriptome Depressive Disorder, Major
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Risk Classification for Interstitial Cystitis/Bladder Pain Syndrome Using Machine Learning Based Predictions.

Urology Apr 25, 2024
OBJECTIVE: To improve diagnosis of interstitial cystitis (IC)/bladder pain syndrome(IC) we hereby developed an improved IC risk classification using machine learning algorithms.
Humans Machine Learning Case-Control Studies Biomarkers Cytokines Cystitis, Interstitial Male Middle Aged Aged Female Risk Assessment Adult
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Identification of novel biomarkers in Hunner's interstitial cystitis using the CIBERSORT, an algorithm based on machine learning.

BMC urology Aug 16, 2021
BACKGROUND:  Hunner's interstitial cystitis (HIC) is a complex disorder characterized by pelvic pain, disrupted urine storage, and Hunner lesions seen on cystoscopy. There are few effective diagnostic biomarkers. In the present study, we used the nov...
Biomarkers Memory T Cells Mast Cells T Follicular Helper Cells Humans CD3 Complex Machine Learning Memory B Cells HLA-DR Antigens CD4 Antigens Killer Cells, Natural Plasma Cells Cystitis, Interstitial
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Repeated intravesical injections of platelet-rich plasma are effective in the treatment of interstitial cystitis: a case control pilot study.

Lower urinary tract symptoms Dec 19, 2017
OBJECTIVE: Interstitial cystitis (IC), also known as bladder pain syndrome (BPS), is a debilitating chronic disease. There are few treatment options for IC/BPS refractory to current medical therapy. This study investigated the clinical efficacy of in...
Pilot Projects Middle Aged Platelet-Rich Plasma Treatment Outcome Administration, Intravesical Humans Case-Control Studies Cystitis, Interstitial Female
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