Journal of chemical information and modeling
Mar 28, 2025
With the breakthroughs in protein structure prediction technology, constructing atomic structures from cryo-electron microscopy (cryo-EM) density maps through structural fitting has become increasingly critical. However, the accuracy of the construct...
Protein sequence design in the context of small molecules, nucleotides and metals is critical to enzyme and small-molecule binder and sensor design, but current state-of-the-art deep-learning-based sequence design methods are unable to model nonprote...
BACKGROUND: The CRISPR-Cas9 system has emerged as one of the most promising gene-editing technologies in biology. However, off-target effects remain a significant challenge. While recent advances in deep learning have led to the development of models...
International journal of molecular sciences
Mar 28, 2025
The control of socioeconomically important parasitic roundworms (nematodes) of animals has become challenging or ineffective due to problems associated with widespread resistance in these worms to most classes of chemotherapeutic drugs (anthelmintics...
Communication barriers pose significant challenges for the Deaf and Hard-of-Hearing (DHH) community, limiting their access to essential services, social interactions, and professional opportunities. To bridge this gap, assistive technologies leveragi...
BACKGROUND: Differentiating chondroid tumors is crucial for proper patient management. This study aimed to develop a deep learning model (DLM) for classifying enchondromas, atypical cartilaginous tumors (ACT), and high-grade chondrosarcomas using CT ...
The kidney plays a vital role in maintaining homeostasis, but lifestyle factors and diseases can lead to kidney failures. Early detection of kidney disease is crucial for effective intervention, often challenging due to unnoticeable symptoms in the i...
Essential tremor (ET) is the most prevalent movement disorder, with its incidence increasing with age, significantly impacting motor functions and quality of life. Traditional methods for assessing ET severity are often time-consuming, subjective, an...
The agricultural industry is experiencing revolutionary changes through the latest advances in artificial intelligence and deep learning-based technologies. These powerful tools are being used for a variety of tasks including crop yield estimation, c...
BackgroundMonkeypox (mpox) is a zoonotic infectious disease caused by the mpox virus and characterized by painful body lesions, fever, headaches, and exhaustion. Since the report of the first human case of mpox in Africa, there have been multiple out...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.