Drug registration requires risk assessment of new active pharmaceutical ingredients or excipients to ensure they are safe for human health and the environment. However, traditional risk assessment is expensive and relies heavily on animal testing. Ma...
IEEE journal of biomedical and health informatics
Dec 5, 2024
4D Flow Magnetic Resonance Imaging (4D Flow MRI) is a non-invasive measurement technique capable of quantifying blood flow across the cardiovascular system. While practical use is limited by spatial resolution and image noise, incorporation of traine...
Accurate prediction of bioaccumulation parameters is essential for assessing exposure, hazards, and risks of chemicals. However, the majority of prediction models on bioaccumulation parameters are individual models based on a single algorithm and lac...
Medical & biological engineering & computing
Oct 28, 2024
Accurate segmentation of the temporomandibular joint (TMJ) from cone beam CT (CBCT) images holds significant clinical value for diagnosing temporomandibular joint osteoarthrosis (TMJOA) and related conditions. Convolutional neural network-based medic...
Computer methods in biomechanics and biomedical engineering
Feb 21, 2024
The death of brain cells occurs when blood flow to a particular area of the brain is abruptly cut off, resulting in a stroke. Early recognition of stroke symptoms is essential to prevent strokes and promote a healthy lifestyle. FAST tests (looking fo...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Nov 15, 2025
Ester and acid aroma compounds are crucial components affecting the fragrance of Baijiu, and their composition can endow the Baijiu with a fruity, acidic, floral, or roasted aroma. This study aims to quantitatively detect the ester and acid content i...
Progress in neuro-psychopharmacology & biological psychiatry
Jun 20, 2025
BACKGROUND: For suicide in major depression disorder, it is urgent to seek for a reliable neuroimaging biomarker with interpretable links to molecular tissue signatures. Accordingly, we developed an ensemble learning scheme over transcriptome-defined...
This study employs Convolutional Neural Networks (CNNs) as feature extractors with appended regression layers for the non-invasive prediction of Cobb Angle (CA) from Surface Topography (ST) scans in adolescents with Idiopathic Scoliosis (AIS). The ai...
IEEE journal of biomedical and health informatics
Jun 1, 2025
Electroencephalogram (EEG) artifact removal has been investigated for decades with the goal of reconstructing the clean signals for the subsequent EEG analysis. However, existing denoising methods still have limited capabilities to handle the highly ...
Cardiovascular diseases (CVDs) are still one of the leading causes of death globally, underscoring the importance of early and right risk prediction for effective preventive measures and therapeutic approaches. This study proposes an innovative hybri...
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