In life cycle assessment, characterization factors are used to convert the amount of the chemicals and other pollutants generated in a product's life cycle to the standard unit of an impact category, such as ecotoxicity. However, as a widely used imp...
Environmental pollution (Barking, Essex : 1987)
Dec 4, 2019
Cypermethrin is a frequently used insecticide in agriculture and households but its chronic and molecular effects are poorly known are . Here we describe effects of sublethal cypermethrin exposure on the global transcriptome in the brain of honey bee...
International journal of environmental research and public health
Jul 25, 2019
Lead, mercury, and cadmium are common environmental pollutants in industrialized countries, but their combined impact on hypercholesterolemia (HC) is poorly understood. The aim of this study was to compare the performance of various machine learning ...
Human well-being can be affected by exposure to several chemicals in the environment. One such group is endocrine disrupting chemicals (EDCs) that can perturb the hormonal homeostasis leading to adverse health effects. In this work, we have developed...
Over 80,000 endocrine-disrupting chemicals (EDCs) are considered emerging contaminants (ECs), which are of great concern due to their effects on human health. Quantitative structure-activity relationship (QSAR) models are a promising alternative to i...
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
Mar 1, 2019
Humans and wildlife inhabit a world with panoply of natural and synthetic chemicals. Alarmingly, only a limited number of chemicals have undergone comprehensive toxicological evaluation due to limitations of traditional toxicity testing. High-through...
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
Jan 10, 2019
In silico toxicity prediction plays an important role in the regulatory decision making and selection of leads in drug design as in vitro/vivo methods are often limited by ethics, time, budget, and other resources. Many computational methods have bee...
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
Jan 10, 2019
We introduce here ML4Tox, a framework offering Deep Learning and Support Vector Machine models to predict agonist, antagonist, and binding activities of chemical compounds, in this case for the estrogen receptor ligand-binding domain. The ML4Tox mode...
Glyphosate is one of the most widely used herbicides in the United States, which has led to its ubiquitous occurrence in food and water and regular detection in human urine at concentrations of 1-10 μg/L. Data pertaining to health risks arising from ...
Despite the fact that many of persistent organic pollutants (POPs) have been banned for decades, they still constitute a group of harmful substances to human health. Prenatal exposure can have adverse effects on one's health as well as on their newbo...
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