AIMC Topic: Prenatal Exposure Delayed Effects

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Air Pollution and Autism Spectrum Disorder: Unveiling Multipollutant Risks and Sociodemographic Influences in California.

Environmental health perspectives
BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental condition with increasing prevalence worldwide. Air pollution may be a major contributor to the rise in ASD cases. This study investigated how the risk of ASD associated with prenatal...

Effect of pregnancy and infancy exposure to outdoor particulate matter (PM, PM, PM) and SO on childhood pneumonia in preschool children in Taiyuan City, China.

Environmental pollution (Barking, Essex : 1987)
There is currently a paucity of research on the effects of early life exposure to particulate matter (PM) of various size fractions on pneumonia in preschool-aged children. We explored the connections between antenatal and postnatal exposure to atmos...

Using machine learning to investigate the influence of the prenatal chemical exposome on neurodevelopment of young children.

Neurotoxicology
Research investigating the prenatal chemical exposome and child neurodevelopment has typically focused on a limited number of chemical exposures and controlled for sociodemographic factors and maternal mental health. Emerging machine learning approac...

A machine-learning exploration of the exposome from preconception in early childhood atopic eczema, rhinitis and wheeze development.

Environmental research
BACKGROUND: Most previous research on the environmental epidemiology of childhood atopic eczema, rhinitis and wheeze is limited in the scope of risk factors studied. Our study adopted a machine learning approach to explore the role of the exposome st...

Large-scale proteomics in the first trimester of pregnancy predict psychopathology and temperament in preschool children: an exploratory study.

Journal of child psychology and psychiatry, and allied disciplines
BACKGROUND: Understanding the prenatal origins of children's psychopathology is a fundamental goal in developmental and clinical science. Recent research suggests that inflammation during pregnancy can trigger a cascade of fetal programming changes t...

Detection of prenatal alcohol exposure using machine learning classification of resting-state functional network connectivity data.

Alcohol (Fayetteville, N.Y.)
Fetal Alcohol Spectrum Disorder (FASD), a wide range of physical and neurobehavioral abnormalities associated with prenatal alcohol exposure (PAE), is recognized as a significant public health concern. Advancements in the diagnosis of FASD have been ...

Machine Learning-Based DNA Methylation Score for Fetal Exposure to Maternal Smoking: Development and Validation in Samples Collected from Adolescents and Adults.

Environmental health perspectives
BACKGROUND: Fetal exposure to maternal smoking during pregnancy is associated with the development of noncommunicable diseases in the offspring. Maternal smoking may induce such long-term effects through persistent changes in the DNA methylome, which...

Association between prenatal exposure to multiple persistent organic pollutants (POPs) and growth indicators in newborns.

Environmental research
Despite the fact that many of persistent organic pollutants (POPs) have been banned for decades, they still constitute a group of harmful substances to human health. Prenatal exposure can have adverse effects on one's health as well as on their newbo...

Prenatal exposure to persistent organic pollutants in Northern Tanzania and their distribution between breast milk, maternal blood, placenta and cord blood.

Environmental research
Human exposure to persistent organic pollutants (POPs) begins during pregnancy and may cause adverse health effects in the fetus or later in life. The present study aimed to assess prenatal POPs exposure to Tanzanian infants and evaluate the distribu...

Call category classification of the isolation-induced ultrasonic vocalizations emitted by BTBR TItpr3/J mouse pups exposed to different perinatal diets.

Brain research
Autism spectrum disorder (ASD) is characterized by deficits in social communication and repetitive behaviors/restricted interests that may be diagnosed as early as 2 years of age. This suggests that the pathology underlying the disorder is present du...