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Escitalopram

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Logic-based machine learning predicts how escitalopram attenuates cardiomyocyte hypertrophy.

Proceedings of the National Academy of Sciences of the United States of America
Cardiomyocyte hypertrophy is a key clinical predictor of heart failure. High-throughput and AI-driven screens have the potential to identify drugs and downstream pathways that modulate cardiomyocyte hypertrophy. Here, we developed LogiRx, a logic-bas...

Optimizing the Prediction of Depression Remission: A Longitudinal Machine Learning Approach.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
Decisions about when to change antidepressant treatment are complex and benefit from accurate prediction of treatment outcome. Prognostic accuracy can be enhanced by incorporating repeated assessments of symptom severity collected during treatment. P...