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Evidence-Based Medicine

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Critical gaps in the medical knowledge base of eating disorders.

Eating and weight disorders : EWD
Eating disorders are unique in that they inherently have much medical comorbidity both as a part of restricting-type eating disorders and those characterized by purging behaviors. Over the last three decades, remarkable progress has been made in the ...

Vitamin D status in relation to Crohn's disease: Meta-analysis of observational studies.

Nutrition (Burbank, Los Angeles County, Calif.)
OBJECTIVES: Inconsistent findings have been published regarding vitamin D status among patients with Crohn's disease (CD) and the association with disease severity. We aimed to perform a meta-analysis evaluating serum 25-hydroxy vitamin D and 1,25 de...

Transoral robotic excision of ectopic lingual thyroid: Case series and literature review.

Head & neck
BACKGROUND: Surgical excision of an ectopic lingual thyroid has traditionally been associated with significant morbidity and has therefore been reserved for patients with severe obstructive symptoms or suspected malignancy. Transoral robotic surgery ...

An approach to fuzzy soft sets in decision making based on grey relational analysis and Dempster-Shafer theory of evidence: An application in medical diagnosis.

Artificial intelligence in medicine
OBJECTIVE: The existing methods of fuzzy soft sets in decision making are mainly based on different kinds of level soft sets, and it is very difficult for decision makers to select a suitable level soft set in most instances. The goal of this paper i...

Automatic evidence quality prediction to support evidence-based decision making.

Artificial intelligence in medicine
BACKGROUND: Evidence-based medicine practice requires practitioners to obtain the best available medical evidence, and appraise the quality of the evidence when making clinical decisions. Primarily due to the plethora of electronically available data...

Variable importance and prediction methods for longitudinal problems with missing variables.

PloS one
We present prediction and variable importance (VIM) methods for longitudinal data sets containing continuous and binary exposures subject to missingness. We demonstrate the use of these methods for prognosis of medical outcomes of severe trauma patie...

Robotic general surgery: current practice, evidence, and perspective.

Langenbeck's archives of surgery
BACKGROUND: Robotic technology commenced to be adopted for the field of general surgery in the 1990s. Since then, the da Vinci surgical system (Intuitive Surgical Inc, Sunnyvale, CA, USA) has remained by far the most commonly used system in this doma...

Automated confidence ranked classification of randomized controlled trial articles: an aid to evidence-based medicine.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: For many literature review tasks, including systematic review (SR) and other aspects of evidence-based medicine, it is important to know whether an article describes a randomized controlled trial (RCT). Current manual annotation is not com...

Evaluating a large language model's ability to answer clinicians' requests for evidence summaries.

Journal of the Medical Library Association : JMLA
OBJECTIVE: This study investigated the performance of a generative artificial intelligence (AI) tool using GPT-4 in answering clinical questions in comparison with medical librarians' gold-standard evidence syntheses.

Towards Autonomous Living Meta-Analyses: A Framework for Automation of Systematic Review and Meta-Analyses.

Studies in health technology and informatics
Systematic review and meta-analysis constitute a staple of evidence-based medicine, an obligatory step in developing the guideline and recommendation document. It is a formalized process aiming at extracting and summarizing knowledge from the publish...