IEEE/ACM transactions on computational biology and bioinformatics
Jan 1, 2015
Searching genomes to locate noncoding RNA genes with known secondary structure is an important problem in bioinformatics. In general, the secondary structure of a searched noncoding RNA is defined with a structure model constructed from the structura...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2015
Essential genes are indispensable for the target organism's survival. Large-scale identification and characterization of essential genes has shown to be beneficial in both fundamental biology and medicine fields. Current existing genome-scale experim...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2015
Computational methods are invaluable when protein sequences, directly derived from genomic data, need functional and structural annotation. Subcellular localization is a feature necessary for understanding the protein role and the compartment where t...