AIMC Topic: Glycyrrhiza

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Unraveling potent Glycyrrhiza glabra flavonoids as AKT1 inhibitors using network pharmacology and machine learning-assisted QSAR.

Molecular diversity May 8, 2025
Glycyrrhiza glabra (G. glabra) phytocompounds have been reported to interact with neurological targets, including those implicated in epilepsy, and may modulate epilepsy-related targets. While substantial evidence supports their potential antiepilept...
Humans Machine Learning Molecular Docking Simulation Flavonoids Proto-Oncogene Proteins c-akt Glycyrrhiza Quantitative Structure-Activity Relationship Protein Kinase Inhibitors Network Pharmacology
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Deep learning-based network pharmacology for exploring the mechanism of licorice for the treatment of COVID-19.

Scientific reports Apr 10, 2023
Licorice, a traditional Chinese medicine, has been widely used for the treatment of COVID-19, but all active compounds and corresponding targets are still not clear. Therefore, this study proposed a deep learning-based network pharmacology approach t...
COVID-19 SARS-CoV-2 Molecular Docking Simulation Deep Learning Glycyrrhiza Angiotensin-Converting Enzyme 2 Network Pharmacology
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Analysis of Licorice () Root Extract Activity on in Comparison to Chlorhexidine and Fluoride Mouthwash.

The journal of contemporary dental practice Dec 1, 2019
AIM: The present study was done to determine the activity of licorice root extract on () in comparison to chlorhexidine and fluoride mouthwash.
Humans Plant Extracts Dental Caries Streptococcus mutans Fluorides Chlorhexidine Glycyrrhiza Mouthwashes
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Hispaglabridin B, a constituent of liquorice identified by a bioinformatics and machine learning approach, relieves protein-energy wasting by inhibiting forkhead box O1.

British journal of pharmacology Dec 4, 2018
BACKGROUND AND PURPOSE: Liquorice is the root of Glycyrrhiza glabra, which is a popular food in Europe and China that has previously shown benefits for skeletal fatigue and nutrient metabolism. However, the mechanism and active ingredients remain lar...
Machine Learning Animals Male Mice Computational Biology Plant Extracts Mice, Inbred C57BL Dose-Response Relationship, Drug Muscle, Skeletal Structure-Activity Relationship Plant Roots Models, Molecular Molecular Structure Benzopyrans Glycyrrhiza Transcription, Genetic Muscular Atrophy Forkhead Box Protein O1
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