AIMC Topic: Hallucinogens

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Spectral signatures of serotonergic psychedelics and glutamatergic dissociatives.

NeuroImage
Classic serotonergic psychedelics are remarkable for their capacity to induce reversible alterations in consciousness of the self and the surroundings, mediated by agonism at serotonin 5-HT receptors. The subjective effects elicited by dissociative d...

Metabolomics predicts the pharmacological profile of new psychoactive substances.

Journal of psychopharmacology (Oxford, England)
BACKGROUND: The unprecedented proliferation of new psychoactive substances (NPS) threatens public health and challenges drug policy. Information on NPS pharmacology and toxicity is, in most cases, unavailable or very limited and, given the large numb...

Chemogenomics knowledgebase and systems pharmacology for hallucinogen target identification-Salvinorin A as a case study.

Journal of molecular graphics & modelling
Drug abuse is a serious problem worldwide. Recently, hallucinogens have been reported as a potential preventative and auxiliary therapy for substance abuse. However, the use of hallucinogens as a drug abuse treatment has potential risks, as the funda...

[Psilocybin in the setting of treatment-resistant unipolar depression: A case report].

L'Encephale
BACKGROUND: Current antidepressants have shown certain limitations in the treatment of unipolar depression. Their long onset of action, interactions, and side effects are obstacles to achieving lasting remission of this prevalent, often chronic or re...

Cyberdelics: Virtual reality hallucinations modulate cognitive-affective processes.

Dialogues in clinical neuroscience
INTRODUCTION: Psychedelics were explored for their potential in the mental health field. However, research was delayed by concerns over short-term side effects and long-term consequences of substance use. Technological advances enabled the developmen...