AIMC Topic: Volatile Organic Compounds
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Exhaled gas biomarkers: a non-invasive approach for distinguishing diabetes and its complications.
The Analyst
Aug 4, 2025
Exhaled gas detection offers a safe, convenient, and non-invasive clinical diagnostic method for preventing the progression of diabetes to complications. In this study, gas chromatography-mass spectrometry (GC-MS) analysis and statistical methods wer...
Non-invasive breath testing to detect colorectal cancer: protocol for a multicentre, case-control development and validation study (COBRA2 study).
BMC cancer
Jul 29, 2025
BACKGROUND: Colorectal cancer (CRC) is the fourth most common cancer in the United Kingdom. The five-year survival rate from CRC is only 10% when discovered at a late stage, but can exceed 90% if diagnosed early. Symptoms related to CRC can be non-sp...
Smart Detection of Food Spoilage Using Microbial Volatile Compounds: Technologies, Challenges, and Future Outlook.
Journal of agricultural and food chemistry
Jul 28, 2025
Microbial volatile organic compounds (MVOCs) serve as early, noninvasive indicators of food spoilage and microbial contamination. This review critically assesses current methods for MVOC detection, including gas chromatography-mass spectrometry (GC-M...
Determination of lung cancer exhaled breath biomarkers using machine learning-a new analysis framework.
Scientific reports
Jul 18, 2025
Exhaled breath samples of lung cancer patients (LC), tuberculosis (TB) patients and asymptomatic controls (C) were analyzed using gas chromatography-mass spectrometry (GC-MS). Ten volatile organic compounds (VOCs) were identified as possible biomarke...
Electronic-Nose Technology for Lung Cancer Detection: A Non-Invasive Diagnostic Revolution.
Lung
Jul 8, 2025
BACKGROUND: Lung cancer (LC) remains a leading cause of cancer-related mortality worldwide, primarily due to late-stage diagnosis and the absence of effective early detection methods.
Breath profiles in paediatric allergic asthma by proton transfer reaction mass spectrometry.
BMJ open respiratory research
Jun 27, 2025
INTRODUCTION: Enhancing paediatric asthma diagnosis is crucial. Molecular analysis of exhaled breath is a rapidly evolving field aimed at harnessing established and innovative technologies for clinical applications. This study evaluates the feasibili...
Exploring the association between volatile organic compound exposure and chronic kidney disease: evidence from explainable machine learning methods.
Renal failure
Jun 23, 2025
BACKGROUND: Chronic Kidney Disease (CKD) affects approximately 697.5 million people worldwide. Volatile organic compounds (VOCs) are emerging as potential risk factors, but their complex relationships with CKD may be underestimated by traditional lin...
Oxygenated Organic Molecules over the Boundary Layer Aloft in Beijing.
Environmental science & technology
Jun 11, 2025
Oxygenated organic molecules (OOMs) originate from both direct emissions and secondary formation via the oxidation of volatile organic compounds (VOCs) emitted from biogenic and anthropogenic sources. OOMs are suggested to play a crucial role in the ...
Towards robust medical machine olfaction: Debiasing GC-MS data enhances prostate cancer diagnosis from urine volatiles.
PloS one
May 30, 2025
Prostate cancer (PCa) is a major, and increasingly global, health concern with current screening and diagnostic tools' severe limitations causing unnecessary, invasive biopsy procedures. While gas chromatography-mass spectrometry (GC-MS) has been use...
An Artificial Intelligence Olfactory-Based Diagnostic Model for Parkinson's Disease Using Volatile Organic Compounds from Ear Canal Secretions.
Analytical chemistry
May 28, 2025
Parkinson's Disease (PD), a frequently diagnosed neurodegenerative condition, poses a major global challenge. Early diagnosis and intervention are crucial for PD treatment. This study proposes a diagnostic model for PD that analyzes volatile organic ...
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