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Infusions, Parenteral

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Caspofungin infusion solutions (50 mg/100 mL): chemical stability and antifungal activity against Candida spp.

Die Pharmazie
BACKGROUND: Ready to use caspofungin infusion bags are centrally prepared in the Hospital Pharmacy, University Hospital of Heidelberg, for economic reasons and possibly occurring problems with drug shortages. The aim of this study was a quality contr...

Optimal adaptive control of drug dosing using integral reinforcement learning.

Mathematical biosciences
In this paper, a reinforcement learning (RL)-based optimal adaptive control approach is proposed for the continuous infusion of a sedative drug to maintain a required level of sedation. To illustrate the proposed method, we use the common anesthetic ...

Analysis of production time and capacity for manual and robotic compounding scenarios for parenteral hazardous drugs.

European journal of hospital pharmacy : science and practice
BACKGROUND: The increasing amount of hazardous preparations in combination with shortages leads to a call for more efficient compounding methods. This research aims to evaluate the required amount of time, production capacity and direct labour costs ...

Machine learning for adverse event prediction in outpatient parenteral antimicrobial therapy: a scoping review.

The Journal of antimicrobial chemotherapy
OBJECTIVE: This study aimed to conduct a scoping review of machine learning (ML) techniques in outpatient parenteral antimicrobial therapy (OPAT) for predicting adverse outcomes and to evaluate their validation, implementation and potential barriers ...