AIMC Topic: Infusions, Parenteral

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Analysis of production time and capacity for manual and robotic compounding scenarios for parenteral hazardous drugs.

European journal of hospital pharmacy : science and practice Jun 21, 2024
BACKGROUND: The increasing amount of hazardous preparations in combination with shortages leads to a call for more efficient compounding methods. This research aims to evaluate the required amount of time, production capacity and direct labour costs ...
Humans Infusions, Parenteral Hazardous Substances Pharmacy Service, Hospital Netherlands Drug Compounding Time Factors Robotics
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Optimal adaptive control of drug dosing using integral reinforcement learning.

Mathematical biosciences Feb 5, 2019
In this paper, a reinforcement learning (RL)-based optimal adaptive control approach is proposed for the continuous infusion of a sedative drug to maintain a required level of sedation. To illustrate the proposed method, we use the common anesthetic ...
Propofol Models, Biological Machine Learning Computer Simulation Infusions, Parenteral Anesthetics, Intravenous Drug Dosage Calculations Humans
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Effectiveness of continuous wound infusion of local anesthetics after abdominal surgeries.

The Journal of surgical research Dec 29, 2016
BACKGROUND: To assess the effectiveness of continuous preperitoneal wound infusion of local anesthetic drug bupivacaine in providing pain relief, reducing opioid consumption, and enhancing postoperative recovery.
Drug Administration Schedule Infusions, Parenteral Infusions, Intralesional Morphine Drug Therapy, Combination Analgesics, Opioid Adult Male Middle Aged Adolescent Aged, 80 and over Young Adult Female Aged Pain Measurement Follow-Up Studies Humans Double-Blind Method Anesthetics, Local Prospective Studies Pain, Postoperative Abdomen Bupivacaine Treatment Outcome
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Machine learning for adverse event prediction in outpatient parenteral antimicrobial therapy: a scoping review.

The Journal of antimicrobial chemotherapy Dec 2, 2024
OBJECTIVE: This study aimed to conduct a scoping review of machine learning (ML) techniques in outpatient parenteral antimicrobial therapy (OPAT) for predicting adverse outcomes and to evaluate their validation, implementation and potential barriers ...
Anti-Infective Agents Drug-Related Side Effects and Adverse Reactions Machine Learning Anti-Bacterial Agents Outpatients Infusions, Parenteral Ambulatory Care Humans Patient Readmission
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Caspofungin infusion solutions (50 mg/100 mL): chemical stability and antifungal activity against Candida spp.

Die Pharmazie Apr 1, 2017
BACKGROUND: Ready to use caspofungin infusion bags are centrally prepared in the Hospital Pharmacy, University Hospital of Heidelberg, for economic reasons and possibly occurring problems with drug shortages. The aim of this study was a quality contr...
Lipopeptides Antifungal Agents Drug Stability Time Factors Caspofungin Chromatography, High Pressure Liquid Microbial Sensitivity Tests Drug Storage Candida Echinocandins Sodium Chloride Pharmaceutical Solutions Infusions, Parenteral
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