Journal of chemical information and modeling
Sep 25, 2025
Traf2-and Nck-interacting kinase (TNIK) has been implicated in fibrosis-associated signaling pathways and has recently emerged as a promising therapeutic target for idiopathic pulmonary fibrosis (IPF). In this study, we employed an integrated strateg...
Journal of chemical information and modeling
Sep 25, 2025
The rapid emergence of drug resistance in viral infections represents a significant global health challenge, threatening the efficacy of treatments for multiple diseases. Machine learning models have emerged as valuable tools for predicting antiviral...
Journal of chemical information and modeling
Sep 25, 2025
The main protease (Mpro) is a critical target in the design of antiviral drugs against coronaviruses, while accurately predicting the binding affinity between small molecules and this target remains a key challenge. In the recent Polaris challenge of...
Oxicams, a major category of nonsteroidal anti-inflammatory drugs, are widely used in daily life. However, excessive consumption of oxicams can pose significant risks to human health. Herein, we introduce an innovative and highly sensitive fluorescen...
BACKGROUND: A multidisciplinary team comprising providers from several specialties is needed for comprehensive cleft care. Although multidisciplinary cleft teams may be readily available in high-income countries, in low- and middle-income countries (...
The 21st-century evolution of hyaluronic acid fillers has brought a diversity of novel aesthetic applications, ranging from static bony augmentation and volume correction to dynamic rhytid effacement and skin revitalization. This rapid advancement ha...
PURPOSE: To study the correctness, completeness, language and readability, and real-world applicability of artificial intelligence chatbots-generated informed consent forms for various ophthalmological procedures and interventions.
Next-generation sequencing (NGS) has revolutionized cancer genomics, offering unparalleled insights into the molecular landscape of various malignancies, including ocular cancers. This review explores the role of NGS in ocular oncology, highlighting ...
Medical healthcare has advanced substantially due to advancements in Artificial Intelligence (AI) techniques for early disease detection alongside support for clinical decisions. However, a gap exists in widespread adoption of results of these algori...
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