International journal of pharmaceutics
Aug 5, 2025
Systemic chemotherapy has long served as a cornerstone in the management of various malignancies. However, its inherent lack of specificity often leads to significant adverse effects, prompting the exploration of innovative nanomedicine strategies to...
The early identification of autism is especially critical as it can significantly enhance the effectiveness of intervention strategies. However, the recognition task remains challenging due to the subtle differences between ASD patients and neurotypi...
ACS biomaterials science & engineering
Aug 5, 2025
Microrobot swarms have attracted significant attention in the biomedical field due to their small size, flexibility, powerful functionality, and ability to collaborate to achieve complex tasks. They show great potential in targeted drug delivery and ...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Aug 5, 2025
Atherosclerosis is a leading cardiovascular disease typified by fatty streaks accumulating within arterial walls, culminating in potential plaque ruptures and subsequent strokes. Existing clinical risk scores, such as systematic coronary risk estimat...
BACKGROUND: Accurate measurement of knee joint range of motion (ROM) is crucial in clinical and rehabilitation settings. Traditional goniometry, which is widely used, requires calibration and is subject to human errors and measurement inconsistencies...
Immune checkpoint inhibitors (ICIs) have changed cancer treatment, evoking durable responses in various cancers. However, their immune-mediated mechanisms can lead to unique toxicities known as immune-related adverse events (irAEs), among which ICI-r...
Monoclonal antibodies are pivotal in modern therapeutics, yet predicting their subcutaneous bioavailability remains challenging due to the intricacies of the SC environment and the limitations of traditional experimental models. In this study, we int...
The global resurgence of dengue presents an ongoing challenge for public health systems, particularly in low- and middle-income countries (LMICs) where conventional early warning systems (EWS) often suffer from reporting delays and under-detection. W...
Neuroscience and biobehavioral reviews
Aug 5, 2025
Substance use disorders (SUD) are chronic, relapsing conditions marked by high variability in treatment response and frequent relapse. This variability arises from complex interactions among behavioral, environmental, and biological factors unique to...
Journal of chemical theory and computation
Aug 5, 2025
Binding free energies are key elements in understanding and predicting the strength of protein-drug interactions. While classical free energy simulations yield good results for many purely organic ligands, drugs, including transition metal atoms, oft...
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