Humans

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Integrating multiple fitting regression and Bayes decision for cancer diagnosis with transcriptomic data from tumor-educated blood platelets.

The Analyst Aug 30, 2017
The application of machine learning in cancer diagnostics has shown great promise and is of importance in clinic settings. Here we consider applying machine learning methods to transcriptomic data derived from tumor-educated platelets (TEPs) from ind...
Reproducibility of Results Neoplasms Transcriptome Humans Algorithms Blood Platelets Support Vector Machine Bayes Theorem
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Computational model for vitamin D deficiency using hair mineral analysis.

Computational biology and chemistry Aug 30, 2017
Vitamin D deficiency is prevalent in the Arabian Gulf region, especially among women. Recent studies show that the vitamin D deficiency is associated with a mineral status of a patient. Therefore, it is important to assess the mineral status of the p...
Mutation Minerals Hair Vitamin D Vitamin D Deficiency Machine Learning Algorithms Female Humans
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Classifying patient portal messages using Convolutional Neural Networks.

Journal of biomedical informatics Aug 30, 2017
OBJECTIVE: Patients communicate with healthcare providers via secure messaging in patient portals. As patient portal adoption increases, growing messaging volumes may overwhelm providers. Prior research has demonstrated promise in automating classifi...
Humans Neural Networks, Computer Computer Graphics Patient Portals Algorithms
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Is Romantic Desire Predictable? Machine Learning Applied to Initial Romantic Attraction.

Psychological science Aug 30, 2017
Matchmaking companies and theoretical perspectives on close relationships suggest that initial attraction is, to some extent, a product of two people's self-reported traits and preferences. We used machine learning to test how well such measures pred...
Personality Sexual Behavior Interpersonal Relations Adult Male Humans Female Young Adult Machine Learning
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Learning-based automated segmentation of the carotid artery vessel wall in dual-sequence MRI using subdivision surface fitting.

Medical physics Aug 30, 2017
PURPOSE: The quantification of vessel wall morphology and plaque burden requires vessel segmentation, which is generally performed by manual delineations. The purpose of our work is to develop and evaluate a new 3D model-based approach for carotid ar...
Machine Learning Automation Image Processing, Computer-Assisted Aged Humans Pattern Recognition, Automated Male Adult Carotid Arteries Magnetic Resonance Imaging
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Rapid Life-Cycle Impact Screening Using Artificial Neural Networks.

Environmental science & technology Aug 30, 2017
The number of chemicals in the market is rapidly increasing, while our understanding of the life-cycle impacts of these chemicals lags considerably. To address this, we developed deep artificial neural network (ANN) models to estimate life-cycle impa...
Global Warming Reproducibility of Results Animals Humans Principal Component Analysis Ecosystem Neural Networks, Computer Environmental Pollutants
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Finding disagreement pathway signatures and constructing an ensemble model for cancer classification.

Scientific reports Aug 30, 2017
Cancer classification based on molecular level is a relatively routine research procedure with advances in high-throughput molecular profiling techniques. However, the number of genes typically far exceeds the number of the sample size in gene expres...
(1)
Anthracyclines Taxoids Atlases as Topic Signal Transduction Support Vector Machine Gene Expression Regulation, Neoplastic Humans Antineoplastic Agents Datasets as Topic Gene Expression Profiling Neoplasms Neoplasm Proteins Oligonucleotide Array Sequence Analysis Gene Regulatory Networks
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All watched over by machines of loving grace: an optimistic view of big data.

BMJ (Clinical research ed.) Aug 30, 2017
Therapeutics Humans Artificial Intelligence
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Semantic Modeling for Exposomics with Exploratory Evaluation in Clinical Context.

Journal of healthcare engineering Aug 30, 2017
Exposome is a critical dimension in the precision medicine paradigm. Effective representation of exposomics knowledge is instrumental to melding nongenetic factors into data analytics for clinical research. There is still limited work in (1) modeling...
(2)
Unified Medical Language System Iatrogenic Disease Environmental Exposure Humans Semantics Pilot Projects Biological Ontologies
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Elastic network model of learned maintained contacts to predict protein motion.

PloS one Aug 30, 2017
We present a novel elastic network model, lmcENM, to determine protein motion even for localized functional motions that involve substantial changes in the protein's contact topology. Existing elastic network models assume that the contact topology r...
Motion Machine Learning Elasticity Arachidonate 15-Lipoxygenase Proteins Animals Protein Conformation Models, Molecular Humans
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