AIMC Topic: Anthracyclines

Clear Filters Showing 1 to 4 of 4 articles

Natural language processing of electronic medical records identifies cardioprotective agents for anthracycline induced cardiotoxicity.

Scientific reports Feb 24, 2025
In this retrospective observational study, we aimed to investigate the potential of natural language processing (NLP) for drug repositioning by analyzing the preventive effects of cardioprotective drugs against anthracycline-induced cardiotoxicity (A...
Retrospective Studies Electronic Health Records Humans Angiotensin Receptor Antagonists Angiotensin-Converting Enzyme Inhibitors Calcium Channel Blockers Hydroxymethylglutaryl-CoA Reductase Inhibitors Anthracyclines Adrenergic beta-Antagonists Cardiotonic Agents Cardiotoxicity Male Middle Aged Drug Repositioning Natural Language Processing Aged Adult Female
View on PubMed DOI

Artificial Intelligence-Enhanced Risk Stratification of Cancer Therapeutics-Related Cardiac Dysfunction Using Electrocardiographic Images.

Circulation. Cardiovascular quality and outcomes Sep 2, 2024
BACKGROUND: Risk stratification strategies for cancer therapeutics-related cardiac dysfunction (CTRCD) rely on serial monitoring by specialized imaging, limiting their scalability. We aimed to examine an application of artificial intelligence (AI) to...
Trastuzumab Cardiotoxicity Predictive Value of Tests Ventricular Dysfunction, Left Anthracyclines Antineoplastic Agents Time Factors United States Electrocardiography Middle Aged Risk Assessment Stroke Volume Risk Factors Aged Male Ventricular Function, Left Retrospective Studies Female Humans Artificial Intelligence
View on PubMed DOI

Deep learning-assisted high-content screening identifies isoliquiritigenin as an inhibitor of DNA double-strand breaks for preventing doxorubicin-induced cardiotoxicity.

Biology direct Oct 9, 2023
BACKGROUND: Anthracyclines including doxorubicin are essential components of many cancer chemotherapy regimens, but their cardiotoxicity severely limits their use. New strategies for treating anthracycline-induced cardiotoxicity (AIC) are still neede...
Doxorubicin Antibiotics, Antineoplastic Cardiotoxicity Anthracyclines Deep Learning DNA Animals Artificial Intelligence
View on PubMed DOI

Finding disagreement pathway signatures and constructing an ensemble model for cancer classification.

Scientific reports Aug 30, 2017
Cancer classification based on molecular level is a relatively routine research procedure with advances in high-throughput molecular profiling techniques. However, the number of genes typically far exceeds the number of the sample size in gene expres...
Datasets as Topic Gene Expression Profiling Anthracyclines Oligonucleotide Array Sequence Analysis Gene Regulatory Networks Taxoids Support Vector Machine Atlases as Topic Gene Expression Regulation, Neoplastic Neoplasm Proteins Neoplasms Signal Transduction Humans Antineoplastic Agents
View on PubMed DOI
Popular Topics
Recent Journals