Journal of chemical information and modeling
Apr 4, 2025
Hydrolysis is a fundamental family of chemical reactions where water facilitates the cleavage of bonds. The process is ubiquitous in biological and chemical systems, owing to water's remarkable versatility as a solvent. However, accurately predicting...
The lignocellulosic biorefinery involves pretreatment, enzymatic hydrolysis, mixed sugar fermentation, and optional anaerobic digestion. This pipeline could be effectively implemented through machine learning (ML)-guided process optimization and stra...
International journal of biological macromolecules
Mar 8, 2025
The simultaneous hydrolysis of cellulose and hemicellulose involves trade-offs, making precise control of hydrolysis products crucial for sustainable development. This study employed three machine learning (ML) models-Random Forest (RF), Extreme Grad...
International journal of biological macromolecules
Feb 16, 2025
Camellia oleifera leaves were byproduct of the C. oleifera industry which was rich in polysaccharides. Deep eutectic solvent-dual enzyme system (DES-dEAE) was established to achieve the simultaneous hydrolysis reaction of dual enzymes and DES extract...
Polysorbate 20 (PS20) is commonly used as an excipient in therapeutic protein formulations. However, over the course of a therapeutic protein product's shelf life, minute amounts of co-purified host-cell lipases may cause slow hydrolysis of PS20, rel...
Food research international (Ottawa, Ont.)
Nov 28, 2024
Industrial wastewaters are significant global concerns due to their environmental impact. Yet, protein-rich wastewaters can be valorized by enzymatic hydrolysis to release bioactive peptides. However, achieving selective molecular differentiation and...
Dissolved organic matter (DOM) is essential in biological treatment, yet its specific roles remain incompletely understood. This study introduces a machine learning (ML) framework to interpret DOM biodegradability in the anaerobic digestion (AD) of s...
Chembiochem : a European journal of chemical biology
Nov 27, 2023
Poly (ethylene terephthalate) (PET) is one of the most commonly used plastics in daily life and various industries. Enzymatic depolymerization and recycling of post-consumer PET (pc-PET) provides a promising strategy for the sustainable circular econ...
An environmentally sustainable method to extract phosphatidylcholine (PC) from chicken liver (PCCL) and its functional properties were studied. The extraction times, enzymatic hydrolysis time, the solid-liquid ratio as well as types of enzymes (prota...
As a class of enzymes, esterases have been investigated for decades and have found use in industrial processes, synthetic organic chemistry, and elsewhere. Esters are functional groups composed of an alcohol moiety and a carboxylic acid moiety. Altho...