Malto-oligosaccharides, structurally diverse glucose polymers comprising 2-10 monosaccharide units, play vital roles in food science, pharmaceuticals, and glycobiology. However, their precise structural characterization remains challenging due to sub...
Biomass is mainly composed of cellulose, hemicellulose, and lignin, where lignin is almost one-third of the amount of biomass. Lignin is removed from the biomass matrix because its complex, recalcitrant structure acts as a physical and chemical barri...
This study aims to develop a comprehensive strategy to investigate whether the integration of ultra-high pressure (UHP)-assisted enzymatic hydrolysis with machine learning and molecular docking can effectively identify salty peptides (SPs) from Litop...
Journal of the American Chemical Society
Jul 8, 2025
Dynamin-related protein (Drp1) drives mitochondrial fission, dysregulation of which leads to neurodegenerative, metabolic, and apoptotic disorders. The precise mechanism of fission completion is unclear. One prevailing model is based on GTP-driven o...
Pretreatment is essential for enhancing sludge treatment efficiency, including anaerobic digestion, phosphorus recovery, sludge dewatering, and heavy metal removal. However, few techniques simultaneously address multiple treatment objectives. In this...
International journal of molecular sciences
May 26, 2025
The active sites of enzymes are able to activate substrates and perform chemical reactions that cannot occur in solutions. We focus on the hydrolysis reactions catalyzed by enzymes and initiated by the nucleophilic attack of the substrate's carbonyl ...
BACKGROUND: Lipomyces starkeyi is an oleaginous yeast with a native metabolism well-suited for production of lipids and biofuels from complex lignocellulosic and waste feedstocks. Recent advances in genetic engineering tools have facilitated the deve...
International journal of biological macromolecules
Apr 30, 2025
Deep eutectic solvents (DESs) are gaining attention for lignocellulose pretreatment, yet screening methods and stable cyclic processes remain underexplored. This study compared solubility and machine learning to predict delignification, screening the...
Journal of chemical information and modeling
Apr 4, 2025
Hydrolysis is a fundamental family of chemical reactions where water facilitates the cleavage of bonds. The process is ubiquitous in biological and chemical systems, owing to water's remarkable versatility as a solvent. However, accurately predicting...
International journal of biological macromolecules
Mar 8, 2025
The simultaneous hydrolysis of cellulose and hemicellulose involves trade-offs, making precise control of hydrolysis products crucial for sustainable development. This study employed three machine learning (ML) models-Random Forest (RF), Extreme Grad...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.