American journal of obstetrics and gynecology
Oct 22, 2020
An increasing number of delivering women experience major morbidity and mortality. Limited work has been done on automated predictive models that could be used for prevention. Using only routinely collected obstetrical data, this study aimed to devel...
Premature babies are at high risk of serious neurodevelopmental disabilities, which in many cases are related to perinatal hypoxic-ischemic encephalopathy (HIE). Studies of neuroprotection in animal models consistently suggest that treatment must be ...
BACKGROUND: Secondary and retrospective use of hospital-hosted clinical data provides a time- and cost-efficient alternative to prospective clinical trials for biomarker development. This study aims to create a retrospective clinical dataset of Magne...
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Jul 25, 2019
OBJECTIVE: Electroencephalogram (EEG) reactivity is a robust predictor of neurological recovery after cardiac arrest, however interrater-agreement among electroencephalographers is limited. We sought to evaluate the performance of machine learning me...
International journal of neural systems
Mar 26, 2019
Hypoxic-ischemic (HI) studies in preterms lack reliable prognostic biomarkers for diagnostic tests of HI encephalopathy (HIE). Our group's observations from fetal sheep models suggest that potential biomarkers of HIE in the form of developing HI mic...
BACKGROUND: The continuation of life-sustaining therapy in critical care patients with anoxic-ischemic disorders of consciousness (AI-DOC) depends on prognostic tests such as serum neuron-specific enolase (NSE) concentration levels.
Automated multimodal prediction of outcome in newborns with hypoxic-ischaemic encephalopathy is investigated in this work. Routine clinical measures and 1h EEG and ECG recordings 24h after birth were obtained from 38 newborns with different grades of...
BACKGROUND: Substantial gaps exist in the neuroprognostication of cardiac arrest patients who remain comatose after the restoration of spontaneous circulation. Most studies focus on predicting survival, a measure confounded by the withdrawal of life-...
Hypoxic-Ischemic Encephalopathy (HIE) occurs in patients who experience a decreased flow of blood and oxygen to the brain, with the optimal window for effective treatment being within the first six hours of life. This puts a significant demand on med...
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