BACKGROUND: In the appropriate clinical setting, the diagnosis of idiopathic pulmonary fibrosis (IPF) requires a pattern of usual interstitial pneumonia to be present on high-resolution chest CT (HRCT) or surgical lung biopsy. A molecular usual inter...
BACKGROUND: Based on international diagnostic guidelines, high-resolution CT plays a central part in the diagnosis of fibrotic lung disease. In the correct clinical context, when high-resolution CT appearances are those of usual interstitial pneumoni...
BACKGROUND The aim of this study was to investigate serum concentrations of visfatin, irisin, and omentin in patients with end-stage lung diseases (ESLD) before and after lung transplantation (LTx) and to find relationship between adipokines levels a...
MOTIVATION: Supervised machine learning is widely applied to transcriptomic data to predict disease diagnosis, prognosis or survival. Robust and interpretable classifiers with high accuracy are usually favored for their clinical and translational pot...
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with few treatment options. The efficacy of N-acetylcysteine in patients with IPF remains controversial. The aim of this research was to investigate the efficacy of inhaled...
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
Jan 12, 2026
Rare lung diseases are a group of diseases characterized by significant clinical heterogeneity, challenging diagnosis and treatment processes, and diverse underlying causes. Due to their uncommon symptoms and limited awareness among healthcare provid...
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Dec 15, 2025
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease in which endothelial cell senescence (ECS) plays a key role. By integrating two GEO transcriptome datasets (145 IPF patients and 84 controls) and applying LASSO, SVM-RFE, ...
OBJECTIVES: To investigate whether a content-based image retrieval (CBIR) of similar chest CT images can help usual interstitial pneumonia (UIP) CT pattern classifications among readers with varying levels of experience.
BACKGROUND: Predicting shorter life expectancy is crucial for prioritising antifibrotic therapy in fibrotic lung diseases (FLDs), where progression varies widely, from stability to rapid deterioration. This heterogeneity complicates treatment decisio...
Progressive lung fibrosis is frequently observed in patients with idiopathic interstitial pneumonias (IIPs), especially in those with idiopathic pulmonary fibrosis (IPF) being a representative form of IIPs characterized by a poor prognosis, even in t...
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