AIMC Topic: Insulin Receptor Substrate Proteins

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Node-based differential network analysis in genomics.

Computational biology and chemistry Apr 4, 2017
Gene dependency networks often undergo changes in response to different conditions. Understanding how these networks change across two conditions is an important task in genomics research. Most previous differential network analysis approaches assume...
Humans Machine Learning Female Breast Neoplasms Gene Regulatory Networks Genomics Ovarian Neoplasms Insulin Receptor Substrate Proteins Proto-Oncogene Proteins c-kit 3-Phosphoinositide-Dependent Protein Kinases Receptor, Notch1 Shc Signaling Adaptor Proteins
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Adaptations to excess choline in insulin resistant and Pcyt2 deficient skeletal muscle.

Biochemistry and cell biology = Biochimie et biologie cellulaire Sep 6, 2016
It was hypothesized that choline supplementation in insulin resistant (IR) CTP:phosphoethanolamine cytidylyltransferase deficient (Pcyt2) mice would ameliorate muscle function by remodeling glucose and fatty acid (FA) metabolism. Pcyt2 mice either re...
Animals Mice Insulin Resistance Signal Transduction Muscle, Skeletal Mice, Knockout Glucose Fatty Acids Administration, Oral Choline Gene Expression Regulation PPAR alpha Triglycerides Microtubule-Associated Proteins Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha Stearoyl-CoA Desaturase Lipogenesis Adaptation, Physiological Carnitine O-Palmitoyltransferase Diacylglycerol O-Acyltransferase Insulin Receptor Substrate Proteins Organic Cation Transport Proteins RNA Nucleotidyltransferases Sterol Regulatory Element Binding Protein 1 fas Receptor
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