AIMC Topic: Stearoyl-CoA Desaturase

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Salidroside sensitizes Triple-negative breast cancer to ferroptosis by SCD1-mediated lipogenesis and NCOA4-mediated ferritinophagy.

Journal of advanced research Sep 29, 2024
INTRODUCTION: Triple-negative breast cancer (TNBC) is the primary cause of breast cancer-induced death in women. Literature has confirmed the benefits of Salidroside (Sal) in treating TNBC. However, the study about potential therapeutic targets and m...
Female Animals Humans Glucosides Ferritins Autophagy Lipogenesis Nuclear Receptor Coactivators Stearoyl-CoA Desaturase Xenograft Model Antitumor Assays Mice, Nude Signal Transduction Phenols Mice Ferroptosis Triple Negative Breast Neoplasms Cell Line, Tumor
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Adaptations to excess choline in insulin resistant and Pcyt2 deficient skeletal muscle.

Biochemistry and cell biology = Biochimie et biologie cellulaire Sep 6, 2016
It was hypothesized that choline supplementation in insulin resistant (IR) CTP:phosphoethanolamine cytidylyltransferase deficient (Pcyt2) mice would ameliorate muscle function by remodeling glucose and fatty acid (FA) metabolism. Pcyt2 mice either re...
RNA Nucleotidyltransferases Sterol Regulatory Element Binding Protein 1 Organic Cation Transport Proteins fas Receptor Carnitine O-Palmitoyltransferase Insulin Receptor Substrate Proteins Diacylglycerol O-Acyltransferase Lipogenesis Mice, Knockout Adaptation, Physiological Fatty Acids Stearoyl-CoA Desaturase Glucose Animals Signal Transduction Mice Muscle, Skeletal Insulin Resistance Triglycerides PPAR alpha Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha Choline Administration, Oral Microtubule-Associated Proteins Gene Expression Regulation
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Salivary sCD14 as a potential biomarker of dental caries activity in adults.

Arhiv za higijenu rada i toksikologiju Dec 20, 2017
CD14 is a co-receptor involved in the recognition of Gram-negative and Gram-positive bacteria, the latter known to cause dental caries. The aim of this study was to determine whether soluble CD14 (sCD14) in saliva was associated with caries activity ...
Dental Caries Saliva Enzyme-Linked Immunosorbent Assay Stearoyl-CoA Desaturase Young Adult Croatia Male Biomarkers Adult Humans Female
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