AIMC Topic: Intervertebral Disc Degeneration

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Identification of KCNQ1 as a diagnostic biomarker related to endoplasmic reticulum stress for intervertebral disc degeneration based on machine learning and experimental evidence.

Medicine
Intervertebral disc degeneration (IDD) is a primary cause of low back pain and disability. Cellular senescence and apoptosis due to endoplasmic reticulum stress (ERS) are key in IDD pathology. Identifying biomarkers linked to ERS in IDD is crucial fo...

A Deep Learning Model for the Accurate and Reliable Classification of Disc Degeneration Based on MRI Data.

Investigative radiology
OBJECTIVES: Although magnetic resonance imaging-based formalized grading schemes for intervertebral disc degeneration offer improved reproducibility compared with purely subjective ratings, their intrarater and interrater reliability are not nearly g...

Efficacy and safety of electroacupuncture in treatment of lumbar disc herniation: a protocol for a cohort study.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
OBJECTIVE: To compare the efficacy of electroacupuncture (deep needling) and general orthopedics in treatment of lumbar disc herniation (LDH), and to evaluate its long-term efficacy.

Development of machine learning algorithms for prediction of discharge disposition after elective inpatient surgery for lumbar degenerative disc disorders.

Neurosurgical focus
OBJECTIVEIf not anticipated and prearranged, hospital stay can be prolonged while the patient awaits placement in a rehabilitation unit or skilled nursing facility following elective spine surgery. Preoperative prediction of the likelihood of postope...

Automated Pathogenesis-Based Diagnosis of Lumbar Neural Foraminal Stenosis via Deep Multiscale Multitask Learning.

Neuroinformatics
Pathogenesis-based diagnosis is a key step to prevent and control lumbar neural foraminal stenosis (LNFS). It conducts both early diagnosis and comprehensive assessment by drawing crucial pathological links between pathogenic factors and LNFS. Automa...

Revisions for screw malposition and clinical outcomes after robot-guided lumbar fusion for spondylolisthesis.

Neurosurgical focus
OBJECTIVE The accuracy of robot-guided pedicle screw placement has been proven to be high, but little is known about the impact of such guidance on clinical outcomes such as the rate of revision surgeries for screw malposition. In addition, there are...