AIMC Topic: Kernicterus

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Integrated machine learning identifies biomarkers for bilirubin-induced Alzheimer's disease-like lesions in neonates and adults.

Scientific reports
Neurological impairments resulting from bilirubin encephalopathy represent a hallmark of bilirubin's neurotoxic effects. Earlier research suggests that bilirubin may contribute to Alzheimer's disease (AD) pathology by inducing neuronal necrosis and a...

Detecting neonatal acute bilirubin encephalopathy based on T1-weighted MRI images and learning-based approaches.

BMC medical imaging
BACKGROUND: Neonatal hyperbilirubinemia is a common clinical condition that requires medical attention in newborns, which may develop into acute bilirubin encephalopathy with a significant risk of long-term neurological deficits. The current clinical...

Detecting acute bilirubin encephalopathy in neonates based on multimodal MRI with deep learning.

Pediatric research
BACKGROUND: Differentiating acute bilirubin encephalopathy (ABE) from non-ABE in neonates with hyperbilirubinemia (HB) from routine magnetic resonance imaging (MRI) is extremely challenging since both conditions demonstrate similar T1 hyperintensitie...