Database : the journal of biological databases and curation
Jan 1, 2020
UNLABELLED: Hypothesis generation is a critical step in research and a cornerstone in the rare disease field. Research is most efficient when those hypotheses are based on the entirety of knowledge known to date. Systematic review articles are common...
Database : the journal of biological databases and curation
Jan 1, 2020
Biological knowledgebases rely on expert biocuration of the research literature to maintain up-to-date collections of data organized in machine-readable form. To enter information into knowledgebases, curators need to follow three steps: (i) identify...
BACKGROUND: Diabetes is a disease that affects the body's ability to produce or use insulin. A total of 425 million people are suffering from diabetes in the world. Of this, more than 16 million people live in the Africa Region, which is estimated to...
Journal of the American Medical Informatics Association : JAMIA
Jan 1, 2020
OBJECTIVE: Detecting adverse drug events (ADEs) and medications related information in clinical notes is important for both hospital medical care and medical research. We describe our clinical natural language processing (NLP) system to automatically...
MOTIVATION: Mirtrons arise from short introns with atypical cleavage by using the splicing mechanism. In the current literature, there is no repository centralizing and organizing the data available to the public. To fill this gap, we developed mirtr...
The advances in high-throughput technologies have enabled high-speed accumulation of omics data, which contain a large amount of genetic variations and their functional information. The integration and deep utilization of those data will be a long-te...
Studies in health technology and informatics
Sep 3, 2019
Informal caregivers often complain about missing knowledge. A knowledge-based personalized educational system is developed, which provides caregiving relatives with the information needed. Yet, evaluation against domain experts indicated, that parts ...
Studies in health technology and informatics
Aug 21, 2019
The evaluation of the validity of a knowledge-based system is of great importance during its development. It determines whether the system represents the experts' knowledge correctly. This is highly important, but also particularly difficult, if the ...
Studies in health technology and informatics
Aug 21, 2019
Prescription information and adverse drug reactions (ADR) are two components of detailed medication instructions that can benefit many aspects of clinical research. Automatic extraction of this information from free-text narratives via Information Ex...
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