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Macaca fascicularis

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Prediction of GABA receptor antagonist-induced convulsion in cynomolgus monkeys by combining machine learning and heart rate variability analysis.

Journal of pharmacological and toxicological methods
Drug-induced convulsion is a severe adverse event; however, no useful biomarkers for it have been discovered. We propose a new method for predicting drug-induced convulsions in monkeys based on heart rate variability (HRV) and a machine learning tech...

Sparse Ensemble Machine Learning to Improve Robustness of Long-Term Decoding in iBMIs.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
This paper presents a novel sparse ensemble based machine learning approach to enhance robustness of intracortical Brain Machine Interfaces (iBMIs) in the face of non-stationary distribution of input neural data across time. Each classifier in the en...

The Effects of Population Tuning and Trial-by-Trial Variability on Information Encoding and Behavior.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Identifying the features of population responses that are relevant to the amount of information encoded by neuronal populations is a crucial step toward understanding population coding. Statistical features, such as tuning properties, individual and ...

A versatile robotic platform for the design of natural, three-dimensional reaching and grasping tasks in monkeys.

Journal of neural engineering
OBJECTIVE: Translational studies on motor control and neurological disorders require detailed monitoring of sensorimotor components of natural limb movements in relevant animal models. However, available experimental tools do not provide a sufficient...

Unsupervised lineage-based characterization of primate precursors reveals high proliferative and morphological diversity in the OSVZ.

The Journal of comparative neurology
Generation of the primate cortex is characterized by the diversity of cortical precursors and the complexity of their lineage relationships. Recent studies have reported miscellaneous precursor types based on observer classification of cell biology f...