AIMC Topic: Machine Learning

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Perspectives and applications of machine learning for evolutionary developmental biology.

Molecular omics
Evolutionary Developmental Biology (Evo-Devo) is an ever-expanding field that aims to understand how development was modulated by the evolutionary process. In this sense, "omic" studies emerged as a powerful ally to unravel the molecular mechanisms u...

Blind prediction of protein B-factor and flexibility.

The Journal of chemical physics
The Debye-Waller factor, a measure of X-ray attenuation, can be experimentally observed in protein X-ray crystallography. Previous theoretical models have made strong inroads in the analysis of beta (B)-factors by linearly fitting protein B-factors f...

A systematic exploration of [Formula: see text] cutoff ranges in machine learning models for protein mutation stability prediction.

Journal of bioinformatics and computational biology
Discerning how a mutation affects the stability of a protein is central to the study of a wide range of diseases. Mutagenesis experiments on physical proteins provide precise insights about the effects of amino acid substitutions, but such studies ar...

[COLONSCORE: THE USE OF MACHINE LEARNING OF BIG DATA TO DETECT COLORECTAL CANCER].

Harefuah
The use of big data is in its first years of entering the medical world. Big data research enables analysis of very large volumes of data, identifying patterns and findings which traditional statistical methods cannot handle. The diagnosis of colorec...