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Microelectrodes

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Unsupervised neural spike sorting for high-density microelectrode arrays with convolutive independent component analysis.

Journal of neuroscience methods
BACKGROUND: Unsupervised identification of action potentials in multi-channel extracellular recordings, in particular from high-density microelectrode arrays with thousands of sensors, is an unresolved problem. While independent component analysis (I...

Stop! border ahead: Automatic detection of subthalamic exit during deep brain stimulation surgery.

Movement disorders : official journal of the Movement Disorder Society
BACKGROUND: Microelectrode recordings along preplanned trajectories are often used for accurate definition of the subthalamic nucleus (STN) borders during deep brain stimulation (DBS) surgery for Parkinson's disease. Usually, the demarcation of the S...

Sparse and Specific Coding during Information Transmission between Co-cultured Dentate Gyrus and CA3 Hippocampal Networks.

Frontiers in neural circuits
To better understand encoding and decoding of stimulus information in two specific hippocampal sub-regions, we isolated and co-cultured rat primary dentate gyrus (DG) and CA3 neurons within a two-chamber device with axonal connectivity via micro-tunn...

Scalable Device for Automated Microbial Electroporation in a Digital Microfluidic Platform.

ACS synthetic biology
Electrowetting-on-dielectric (EWD) digital microfluidic laboratory-on-a-chip platforms demonstrate excellent performance in automating labor-intensive protocols. When coupled with an on-chip electroporation capability, these systems hold promise for ...