Deep Brain Stimulation (DBS) of the SubThalamic Nucleus (STN) is effective in alleviating motor symptoms in medication-refractory patients with Parkinson's Disease (PD). Intraoperative identification of the STN relies on MicroElectrode Recordings (ME...
. Biological neural networks (BNNs) are characterized by complex interregional connectivity, allowing for seamless communication between different brain regions.models traditionally consist of single-dish neural cultures that cannot recapitulate the ...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2022
Implanted microelectrode arrays can directly pick up electrode signals from the primary motor cortex (M1) during movement, and brain-machine interfaces (BMIs) can decode these signals to predict the directions of contemporaneous movements. However, i...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Nov 1, 2021
This paper proposes an interactive analysis and visualization tool for the accuracy improvement of electrode placement during neurostimulation therapy surgery. During the procedure, the presented system assists the surgeon in the crucial tissue type ...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2020
Brain-machine interfaces (BMIs) allow individuals to communicate with computers using neural signals, and Kalman Filter (KF) are prevailingly used to decode movement directions from these neural signals. In this paper, we implemented a multi-layer lo...
BACKGROUND: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a proven and effective therapy for the management of the motor symptoms of Parkinson's disease (PD). While accurate positioning of the stimulating electrode is critical for ...
We implemented an automated and efficient open-source software for the analysis of multi-site neuronal spike signals. The software package, named SPICODYN, has been developed as a standalone windows GUI application, using C# programming language with...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2017
With the latest development in the design and fabrication of high-density Multi-Electrode Arrays (MEA) for in-vivo neural recordings, the spatiotemporal information in the recorded signals allows for refined estimation of a neuron's location around t...
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
Aug 1, 2016
Due to the sparsity of brain encoding,the neural ensemble signals recorded by microelectrode arrays contain a lot of noise and redundant information,which could reduce the stability and precision of decoding of motion intent.To solve this problem,we ...
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