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Mechanism-Based and Input-Output Modeling of the Key Neuronal Connections and Signal Transformations in the CA3-CA1 Regions of the Hippocampus.

Neural computation
This letter examines the results of input-output (nonparametric) modeling based on the analysis of data generated by a mechanism-based (parametric) model of CA3-CA1 neuronal connections in the hippocampus. The motivation is to obtain biological insig...

Convergent Time-Varying Regression Models for Data Streams: Tracking Concept Drift by the Recursive Parzen-Based Generalized Regression Neural Networks.

International journal of neural systems
One of the greatest challenges in data mining is related to processing and analysis of massive data streams. Contrary to traditional static data mining problems, data streams require that each element is processed only once, the amount of allocated m...

Stochastic spike synchronization in a small-world neural network with spike-timing-dependent plasticity.

Neural networks : the official journal of the International Neural Network Society
We consider the Watts-Strogatz small-world network (SWN) consisting of subthreshold neurons which exhibit noise-induced spikings. This neuronal network has adaptive dynamic synaptic strengths governed by the spike-timing-dependent plasticity (STDP). ...

Neural coding in the visual system of Drosophila melanogaster: How do small neural populations support visually guided behaviours?

PLoS computational biology
All organisms wishing to survive and reproduce must be able to respond adaptively to a complex, changing world. Yet the computational power available is constrained by biology and evolution, favouring mechanisms that are parsimonious yet robust. Here...

Fuzzy neuronal model of motor control inspired by cerebellar pathways to online and gradually learn inverse biomechanical functions in the presence of delay.

Biological cybernetics
Contrary to forward biomechanical functions, which are deterministic, inverse biomechanical functions are generally not. Calculating an inverse biomechanical function is an ill-posed problem, which has no unique solution for a manipulator with severa...

Hebbian Learning in a Random Network Captures Selectivity Properties of the Prefrontal Cortex.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Complex cognitive behaviors, such as context-switching and rule-following, are thought to be supported by the prefrontal cortex (PFC). Neural activity in the PFC must thus be specialized to specific tasks while retaining flexibility. Nonlinear "mixed...

Flexible three-dimensional artificial synapse networks with correlated learning and trainable memory capability.

Nature communications
If a three-dimensional physical electronic system emulating synapse networks could be built, that would be a significant step toward neuromorphic computing. However, the fabrication complexity of complementary metal-oxide-semiconductor architectures ...

Multi-layer network utilizing rewarded spike time dependent plasticity to learn a foraging task.

PLoS computational biology
Neural networks with a single plastic layer employing reward modulated spike time dependent plasticity (STDP) are capable of learning simple foraging tasks. Here we demonstrate advanced pattern discrimination and continuous learning in a network of s...

Relating dynamic brain states to dynamic machine states: Human and machine solutions to the speech recognition problem.

PLoS computational biology
There is widespread interest in the relationship between the neurobiological systems supporting human cognition and emerging computational systems capable of emulating these capacities. Human speech comprehension, poorly understood as a neurobiologic...

Stimulus-induced transitions between spike-wave discharges and spindles with the modulation of thalamic reticular nucleus.

Journal of computational neuroscience
It is believed that thalamic reticular nucleus (TRN) controls spindles and spike-wave discharges (SWD) in seizure or sleeping processes. The dynamical mechanisms of spatiotemporal evolutions between these two types of activity, however, are not well ...