AI Medical Compendium Topic:
Models, Statistical

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A new computational account of cognitive control over reinforcement-based decision-making: Modeling of a probabilistic learning task.

Neural networks : the official journal of the International Neural Network Society
Recent work on decision-making field offers an account of dual-system theory for decision-making process. This theory holds that this process is conducted by two main controllers: a goal-directed system and a habitual system. In the reinforcement lea...

Multimodal probabilistic generative models for time-course gene expression data and Gene Ontology (GO) tags.

Mathematical biosciences
We propose four probabilistic generative models for simultaneously modeling gene expression levels and Gene Ontology (GO) tags. Unlike previous approaches for using GO tags, the joint modeling framework allows the two sources of information to comple...

Accurate contact predictions using covariation techniques and machine learning.

Proteins
Here we present the results of residue-residue contact predictions achieved in CASP11 by the CONSIP2 server, which is based around our MetaPSICOV contact prediction method. On a set of 40 target domains with a median family size of around 40 effectiv...

Protein contact prediction by integrating joint evolutionary coupling analysis and supervised learning.

Bioinformatics (Oxford, England)
MOTIVATION: Protein contact prediction is important for protein structure and functional study. Both evolutionary coupling (EC) analysis and supervised machine learning methods have been developed, making use of different information sources. However...

The potential of random forest and neural networks for biomass and recombinant protein modeling in Escherichia coli fed-batch fermentations.

Biotechnology journal
Product quality assurance strategies in production of biopharmaceuticals currently undergo a transformation from empirical "quality by testing" to rational, knowledge-based "quality by design" approaches. The major challenges in this context are the ...

Cost-efficient FPGA implementation of basal ganglia and their Parkinsonian analysis.

Neural networks : the official journal of the International Neural Network Society
The basal ganglia (BG) comprise multiple subcortical nuclei, which are responsible for cognition and other functions. Developing a brain-machine interface (BMI) demands a suitable solution for the real-time implementation of a portable BG. In this st...

Rediscovery of Good-Turing estimators via Bayesian nonparametrics.

Biometrics
The problem of estimating discovery probabilities originated in the context of statistical ecology, and in recent years it has become popular due to its frequent appearance in challenging applications arising in genetics, bioinformatics, linguistics,...

Towards dropout training for convolutional neural networks.

Neural networks : the official journal of the International Neural Network Society
Recently, dropout has seen increasing use in deep learning. For deep convolutional neural networks, dropout is known to work well in fully-connected layers. However, its effect in convolutional and pooling layers is still not clear. This paper demons...

Combining knowledge- and data-driven methods for de-identification of clinical narratives.

Journal of biomedical informatics
A recent promise to access unstructured clinical data from electronic health records on large-scale has revitalized the interest in automated de-identification of clinical notes, which includes the identification of mentions of Protected Health Infor...

Matrix measure method for global exponential stability of complex-valued recurrent neural networks with time-varying delays.

Neural networks : the official journal of the International Neural Network Society
In this paper, based on the matrix measure method and the Halanay inequality, global exponential stability problem is investigated for the complex-valued recurrent neural networks with time-varying delays. Without constructing any Lyapunov functions,...