AIMC Topic: Monte Carlo Method

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Is deep learning-enabled real-time personalized CT dosimetry feasible using only patient images as input?

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: To propose a novel deep-learning based dosimetry method that allows quick and accurate estimation of organ doses for individual patients, using only their computed tomography (CT) images as input.

Empirical validation of Conformal Prediction for trustworthy skin lesions classification.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Uncertainty quantification is a pivotal field that contributes to realizing reliable and robust systems. It becomes instrumental in fortifying safe decisions by providing complementary information, particularly within high-r...

NPEX: Never give up protein exploration with deep reinforcement learning.

Journal of molecular graphics & modelling
Elucidating unknown structures of proteins, such as metastable states, is critical in designing therapeutic agents. Protein structure exploration has been performed using advanced computational methods, especially molecular dynamics and Markov chain ...

Refining the rheological characteristics of high drug loading ointment via SDS and machine learning.

PloS one
This paper presents an optimized preparation process for external ointment using the Definitive Screening Design (DSD) method. The ointment is a Traditional Chinese Medicine (TCM) formula developed by Professor WYH, a renowned TCM practitioner in Jia...

A deep-learning-based scatter correction with water equivalent path length map for digital radiography.

Radiological physics and technology
We proposed a new deep learning (DL) model for accurate scatter correction in digital radiography. The proposed network featured a pixel-wise water equivalent path length (WEPL) map of subjects with diverse sizes and 3D inner structures. The proposed...

Deep learning for high-resolution dose prediction in high dose rate brachytherapy for breast cancer treatment.

Physics in medicine and biology
Monte Carlo (MC) simulations are the benchmark for accurate radiotherapy dose calculations, notably in patient-specific high dose rate brachytherapy (HDR BT), in cases where considering tissue heterogeneities is critical. However, the lengthy computa...

Optimisation and Calibration of Bayesian Neural Network for Probabilistic Prediction of Biogas Performance in an Anaerobic Lagoon.

Sensors (Basel, Switzerland)
This study aims to enhance diagnostic capabilities for optimising the performance of the anaerobic sewage treatment lagoon at Melbourne Water's Western Treatment Plant (WTP) through a novel machine learning (ML)-based monitoring strategy. This strate...

Aleatoric and epistemic uncertainty extraction of patient-specific deep learning-based dose predictions in LDR prostate brachytherapy.

Physics in medicine and biology
In brachytherapy, deep learning (DL) algorithms have shown the capability of predicting 3D dose volumes. The reliability and accuracy of such methodologies remain under scrutiny for prospective clinical applications. This study aims to establish fast...

Deep-Learning for Rapid Estimation of the Out-of-Field Dose in External Beam Photon Radiation Therapy - A Proof of Concept.

International journal of radiation oncology, biology, physics
PURPOSE: The dose deposited outside of the treatment field during external photon beam radiation therapy treatment, also known as out-of-field dose, is the subject of extensive study as it may be associated with a higher risk of developing a second c...