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Nanomedicine

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Multi-Responsive Bottlebrush-Like Unimolecules Self-Assembled Nano-Riceball for Synergistic Sono-Chemotherapy.

Small methods
Improved drug loading content, bioavailability, and controlled release in targeted tissue have been major bottlenecks in the design of precision nanomedicine. Herein, a tumor-specific and multiple-stimuli responsive nano-riceball is proposed and vali...

Artificial Intelligence and Machine Learning in Computational Nanotoxicology: Unlocking and Empowering Nanomedicine.

Advanced healthcare materials
Advances in nanomedicine, coupled with novel methods of creating advanced materials at the nanoscale, have opened new perspectives for the development of healthcare and medical products. Special attention must be paid toward safe design approaches fo...

Robotic DNA Nanostructures.

ACS synthetic biology
Over the past decade, DNA nanotechnology has spawned a broad variety of functional nanostructures tailored toward the enabled state at which applications are coming increasingly in view. One of the branches of these applications is in synthetic biolo...

Harnessing adaptive novelty for automated generation of cancer treatments.

Bio Systems
Nanoparticles have the potential to modulate both the pharmacokinetic and pharmacodynamic profiles of drugs, thereby enhancing their therapeutic effect. The versatility of nanoparticles allows for a wide range of customization possibilities. However,...

Engineering microrobots for targeted cancer therapies from a medical perspective.

Nature communications
Systemic chemotherapy remains the backbone of many cancer treatments. Due to its untargeted nature and the severe side effects it can cause, numerous nanomedicine approaches have been developed to overcome these issues. However, targeted delivery of ...

The Role of Machine Learning in Centralized Authorization Process of Nanomedicines in European Union.

Current topics in medicinal chemistry
BACKGROUND: Machine Learning (ML) has experienced an increasing use, given the possibilities to expand the scientific knowledge of different disciplines, such as nanotechnology. This has allowed the creation of Cheminformatic models capable of predic...

A concise review: the synergy between artificial intelligence and biomedical nanomaterials that empowers nanomedicine.

Biomedical materials (Bristol, England)
Nanomedicine has recently experienced unprecedented growth and development. However, the complexity of operations at the nanoscale introduces a layer of difficulty in the clinical translation of nanodrugs and biomedical nanotechnology. This problem i...

Artificial intelligence-powered microfluidics for nanomedicine and materials synthesis.

Nanoscale
Artificial intelligence (AI) is an emerging technology with great potential, and its robust calculation and analysis capabilities are unmatched by traditional calculation tools. With the promotion of deep learning and open-source platforms, the thres...

Current understanding of biological interactions and processing of DNA origami nanostructures: Role of machine learning and implications in drug delivery.

Biotechnology advances
DNA origami has emerged as an exciting avenue that provides a versatile two and three-dimensional DNA-based platform for nanomedicine and drug delivery applications. Their incredible programmability, custom synthesis, efficiency, biocompatibility, an...

Re-envisioning the design of nanomedicines: harnessing automation and artificial intelligence.

Expert opinion on drug delivery
INTRODUCTION: Interest in nanomedicines has surged in recent years due to the critical role they have played in the COVID-19 pandemic. Nanoformulations can turn promising therapeutic cargo into viable products through improvements in drug safety and ...