AIMC Topic: Nefopam

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Physicochemical stability of nefopam and nefopam/droperidol solutions in polypropylene syringes for intensive care units.

European journal of hospital pharmacy : science and practice Jun 11, 2019
INTRODUCTION: Nefopam has been reported to be effective in postoperative pain control with an opioid-sparing effect, but the use of nefopam can lead to nausea and vomiting. To prevent these side effects, droperidol can be mixed with nefopam. In inten...
Humans Intensive Care Units Chromatography, High Pressure Liquid Chemical Phenomena Polypropylenes Syringes Droperidol Nefopam Pharmaceutical Solutions
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Effects of nefopam on emergence agitation after general anesthesia for nasal surgery: A prospective, randomized, and controlled trial.

Medicine Nov 1, 2017
BACKGROUND: Emergence agitation (EA) occurs frequently after nasal surgery. N-methyl-D-aspartate (NMDA) receptor antagonists and analgesics, such as fentanyl, have been shown to prevent EA. Nefopam inhibits the NMDA receptor and shows a potent analge...
Humans Prospective Studies Female Adult Male Middle Aged Incidence Time Factors Treatment Outcome Anesthesia, General Double-Blind Method Heart Rate Nefopam Postoperative Period Airway Extubation Analgesics, Non-Narcotic Emergence Delirium Nasal Surgical Procedures
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